Candida parapsilosis is a well-described causative agent for the delayed onset of postoperative endophthalmitis.1 We present a case demonstrating successful treatment of chronic postsurgical C parapsilosis with oral fluconazole after the proven failure of intravitreal amphotericin B and systemic ketoconazole.
Report of a Case.
A 79-year-old woman presented with a 2-month history of inflammation and decreased vision in her left eye. She had undergone extracapsular cataract extraction with posterior capsular rupture and vitreous loss in the left eye 6 months earlier. A limited anterior vitrectomy with anterior chamber lens implantation was done primarily, and the patient recovered visual acuity of 20/60. The patient had been treated with periocular depot and topical steroids for 4 weeks prior to referral.On examination, visual acuity was 20/400 OS. The results of a biomicroscopic examination revealed 3+ inflammatory cells in the anterior chamber, large keratic precipitates, dense vitreous inflammation, and fragments of
Borne MJ, Elliott JH, O'Day DM. Ocular Fluconazole Treatment of Candida parapsilosis Endophthalmitis After Failed Intravitreal Amphotericin B. Arch Ophthalmol. 1993;111(10):1326-1327. doi:10.1001/archopht.1993.01090100032019