We tested a new stroboscopic light source for intraoperative fluorescein angiography. A pulsed xenon light source and narrow-band interference filters are coupled to a 20-gauge endoilluminator and a 35-mm camera mounted on a surgical microscope. The system was tested with good success in a patient undergoing penetrating keratoplasty. An 18- to 22-μJ flash of 2 milliseconds' duration is achieved, which is well below the safety threshold level. This new stroboscopic light source provides a flash of sufficient light intensity to perform high-resolution, high-contrast fluorescein angiography during operations for the removal of opacified media.
Krueger RR, Morales RB, Smith RE, Sliney DH, Chong LP. New Stroboscopic Light Source for Intraoperative Retinal Fluorescein Angiography. Arch Ophthalmol. 1994;112(3):420-422. doi:10.1001/archopht.1994.01090150152038