B-cell lymphoma is mainly a disease of middle-aged or older individuals. The ocular involvement in primary disease of the central nervous system (CNS) has been recorded in up to 25% of affected adults.1,2 Involvement of the eyes in CNS disease in children has not yet been reported, to our knowledge.
Report of a Case.
A 3-year-old Bedouin boy was admitted to the hospital because of progressive left hemiparesis, malaise, vomiting, and weight loss. The ophthalmologic examination showed mild cell and flare in the anterior chamber of the right eye and few posterior synechiae. The left anterior chamber was normal. In the vitreous of both eyes were moderate cellular infiltrates. Snowball-like white exudates were observed in the peripheral inferior vitreous. There was papilledema of both optic nerve heads. There were bilateral massive, wide, white infiltrates extending from the optic disc to the periphery, covering about half of the total fundus
Wender A, Adar A, Maor E, Yassur Y. Primary B-Cell Lymphoma of the Eyes and Brain in a 3-Year-Old Boy. Arch Ophthalmol. 1994;112(4):450-451. doi:10.1001/archopht.1994.01090160024009