The oustanding article by McCulloch and Skarf1 published in the April 1994 issue of the Archives addresses two important issues: (1) Can the efficacy of early intervention in infants with unilateral, congenital cataracts be followed up through the longitudinal changes in visual evoked potentials (VEPs)? and (2) Which is the most reliable parameter of pattern reversal VEPs for clinical use?
At the end of this nicely designed study, the authors state that VEPs are useful for monitoring visual function after occlusion therapy and "threshold check size has the greatest clinical use." Therefore, from a clinical point of view, VEPs should be considered an "early indicator of poor compliance and/or of the presence of complications affecting visual development."
With regard to the clinical use of this technique, we would like to raise three points. First, it is our personal experience that the reported rapid maturation in VEPs during the first
Nucci P, Brancato R. Pattern Reversal Visual Evoked Potentials Following Early Treatment of Unilateral, Congenital Cataract. Arch Ophthalmol. 1995;113(4):404-405. doi:10.1001/archopht.1995.01100040018009