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Article
April 1995

Bilateral Macular Vitelliform Lesions in a Thrombocytopenic Patient

Author Affiliations

Baltimore, Md

Arch Ophthalmol. 1995;113(4):411-413. doi:10.1001/archopht.1995.01100040025016
Abstract

The appearance of a unilateral posttraumatic yellow maculopathy resembling Best's macular dystrophy after subretinal and subretinal pigment epithelial hemorrhages has been reported.1 We describe herein a thrombocytopenic patient in whom bilateral macular vitelliform lesions developed 4 weeks after sustaining preretinal and intraretinal hemorrhages following a Valsalva maneuver.

Report of a Case.  A 31-year-old black woman with an unremarkable medical and ocular history presented with a 1-week history of menorrhagia, fatigue, and decreased visual acuity in both eyes. Her visual acuity acutely deteriorated bilaterally after attempting to move a refrigerator; visual acuity 1 month prior to this episode was 20/20 OU. She was admitted to the medical intensive care unit of The Johns Hopkins Hospitals with a hematocrit of 0.24 and a platelet count of 16×109/L. The diagnosis of Di Guglielmo's syndrome (autoimmune-mediated destruction of erythrocytes and platelets) was made after the evaluation of bone marrow aspirate and

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