To determine whether a chorioretinal venous anastomosis could be created in humans and to evaluate the influence this has on patients with non-ischemic central retinal vein occlusions in whom progressive visual loss developed.
A total of 24 patients with nonischemic central retinal vein occlusions and progressive visual loss.
An attempt was made to create a chorioretinal venous anastomosis using laser photocoagulation to enable obstructed venous blood to enter the choroid, thus bypassing the site of occlusion.
Main Outcome Measures:
Visual acuity, fundoscopic appearance, and rapid sequence fluorescein angiograms.
A successful chorioretinal venous anastomosis was created in eight cases (33%), with improvement in visual acuity and resolution of the funduscopic appearance of venous occlusion in all eight cases. Of the 16 patients (67%) in whom an anastomosis was not successfully created, the ischemic form of central retinal vein occlusion developed in five (31%), and eight (50%) were left with various degrees of macular damage and reduced visual acuity.
Peripheral chorioretinal venous anastomoses can be created in a nonischemic central retinal vein occlusion and appear to be well tolerated. This technique may have some value in the treatment of patients with this condition; however, to address this fully, a properly constructed randomized prospective clinical trial will need to be performed.
McAllister IL, Constable IJ. Laser-Induced Chorioretinal Venous Anastomosis for Treatment of Nonischemic Central Retinal Vein Occlusion. Arch Ophthalmol. 1995;113(4):456-462. doi:10.1001/archopht.1995.01100040072030