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August 1995

Experimental Globe Rupture After Excimer Laser Photorefractive Keratectomy

Author Affiliations

From the Cornea Consultation Service, Montefiore Medical Center and Bronx-Lebanon Hospital Center, Bronx, NY, and the Department of Ophthalmology, Albert Einstein College of Medicine, New York, NY. Dr Hersh is a principal investigator for Summit Technology Inc. Other authors have no commercial or proprietary interest in any of the instruments or methods described in this report.

Arch Ophthalmol. 1995;113(8):1056-1059. doi:10.1001/archopht.1995.01100080108037

Objective:  To assess corneal weakening after photorefractive keratectomy.

Methods:  Photorefractive keratectomy was performed in 16 human eye-bank eyes by means of a 193-nm excimer laser (range, 6 to 54 diopters [D]). Porcine eyes underwent either photorefractive keratectomy procedures (range, 30 to 93 D) with a 5-mm beam diameter or deep 5-mm plano disc ablations. Intraocular pressure was increased gradually with the use of nitrogen gas until the globe ruptured.

Results:  Human eyes with less than 42 D of correction ruptured at the limbus or behind the insertions of the extraocular muscles. Two eyes showed initial leakage at the 42-D ablation site. Ablations greater than 46 D entered the anterior chamber during treatment. One porcine eye ruptured at the ablation site after a 42-D treatment. Other eyes ruptured at the equator with treatments up to 78 D.

Conclusion:  Excimer laser photorefractive keratectomy does not weaken the cornea after degrees of ablation commonly used in the clinical setting.