Osteogenic sarcoma is a malignant bony tumor of mesenchymal cell ori gin. The association of osteogenic sarcoma with Paget's disease of the bone (osteitis deformans) is well-known. However, orbital involvement is rare; only two other cases have been reported in all of the literature. Untreated, the tumor is lethal, with death usually occurring from extension into the cranial fossa.
Report of a Case.
A 58-year-old man was seen for a 1-month history of diplopia, pain on eye movement, and left upper eyelid ptosis. Of significance in his medical history was Paget's disease of the bone for 23 years and no prior radiation therapy. A review of systems was unremarkable.The ophthalmic evaluation revealed a best-corrected visual acuity of 20/30 OD and 20/80 OS. The left eyelid demonstrated 3 mm of ptosis. Additionally, a 3-mm axial proptosis was present, and the globe was displaced 8 mm laterally and 4 mm inferiorly.
Trevisani MG, Fry CL, Hesse RJ, Willis GW. A Rare Case of Orbital Osteogenic Sarcoma. Arch Ophthalmol. 1996;114(4):494-495. doi:10.1001/archopht.1996.01100130490031