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April 1996

Neural Rim Area Declines With Increased Intraocular Pressure in Urban Americans-Reply

Author Affiliations

Los Angeles, Calif
Baltimore, Md

Arch Ophthalmol. 1996;114(4):500. doi:10.1001/archopht.1996.01100130496035

In reply  We thank Dr Shin for his interest in our article. Dr Shin suggests that a component of the decline in neural rim area with increasing IOP in individuals without any evidence of glaucomatous optic neuropathy is, at least in part, due to mechanical compliance of the optic disc. As evidence of this phenomenon of IOP-related mechanical compliance of the optic disc, Dr Shin cites Parrow et al.1 In that study, a group of 17 patients with glaucoma had optic disc imaging performed at three consecutive time points: low IOP, high IOP, and subsequent low IOP. The measured neural rim area changed by 16% to 23% for a 10 mm Hg change in IOP. This change was attributed to mechanical compliance of the disc. Dr Shin suggests that the results of Parrow et al on a selected group of clinic-based patients with glaucoma can be generalized to our

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