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The goals of my contribution to the Mechanisms of Ophthalmic Disease series were to review recent advances in our understanding of cellular and molecular mechanisms of retinal degenerations and to discuss possible avenues for research into new therapeutic strategies for these devastating disorders. It would have been beyond the scope and space limitations of the article to review the literature on previously described or proposed therapeutic approaches, such as the use of vitamin A in RP or antioxidant treatments for macular degeneration. The opening sentence of my article was actually meant to indicate that no cure is currently available for these diseases, but Dr Crane's comments suggest that the wording of that statement was ambiguous. I would like to thank Dr Crane very much for pointing this out, and for the opportunity to clarify such possible misunderstanding.
Adler R. Mechanisms of Photoreceptor Death in Retinal Degenerations: From the Cell Biology of the 1990s to the Ophthalmology of the 21 st Century?-Reply. Arch Ophthalmol. 1996;114(9):1158. doi:10.1001/archopht.1996.01100140360029