Progressive bilateral enophthalmos in the absence of previous trauma is rare.
Three patients with progressive bilateral severe enophthalmos whose only significant medical history was that of congenital hydrocephalus were treated by ventriculoperitoneal shunt placement.
The patients demonstrated severe bilateral en-ophthalmos with poor eyelid apposition to the globes, resulting in superficial keratopathy. Orbital computed tomographic scans confirmed the severe enophthalmos, with apparent reduced orbital fat volume. Orbital bony anatomy appeared normal.
Bilateral progressive enophthalmos may be associated with hydrocephalus and ventriculoperitoneal shunting. The causal mechanism remains speculative.
Meyer DR, Nerad JA, Newman NJ, Lin JC. Bilateral Enophthalmos Associated With Hydrocephalus and Ventriculoperitoneal Shunting. Arch Ophthalmol. 1996;114(10):1206-1209. doi:10.1001/archopht.1996.01100140406007