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October 1996

Lipemia Retinalis of Prematurity

Author Affiliations

Mie, Japan

Arch Ophthalmol. 1996;114(10):1283-1284. doi:10.1001/archopht.1996.01100140483027

Lipemia retinalis, first described by Heyl1 in 1880, is characterized by creamy white retinal blood vessels, which are caused by hypertriglyceridemia (a triglyceride concentration >28.22 mmol/L [>2500 mg/dL]).2 To the best of our knowledge, lipemia retinalis in a premature neonate has not been previously reported. We successfully treated a neonate born prematurely with lipemia retinalis and hypertriglyceridemia using medium-chain triglyceride (MCT) milk.

Report of a Case.  A Japanese male infant was born prematurely on May 12, 1995. His birth weight was 816 g, and the gestational age was 31 weeks. The administration of cow's milk was started. At 4 weeks of age, no abnormalities were seen in the ocular position, the light reflex, and the anterior segment of either eye. Fundus examination disclosed a bilateral stage 1, zone 2 retinopathy of prematurity by international classification. The peripheral retinal vessels were creamy white. At 6 weeks of age, the

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