Cancers metastatic to the iris or ciliary body are rare.1,2 The most common carcinomas that metastasize to these structures arise in the breast, lung, or kidney.1,2 Malignant müllerian mixed tumors (MMTs) are rare, biphasic neoplasms of the uterus, cervix, and ovaries, and they contain both malignant glandular and stromal components, often including cartilage.3 We recently examined a patient with an MMT metastatic to the iris and ciliary body.
Report of a Case.
A 66-year-old woman complained of pain around her left eye for 2 weeks. Her right eye was clinically unremarkable (bestcorrected visual acuity, 20/50). Examination of her left eye showed a nodular tumor on the anterior surface of the iris between the 3- and 6-o'clock position, which contacted the posterior corneal surface and extended into the chamber angle (Figure 1).The patient's medical history was notable for a hysterectomy, with a bilateral salpingo-oophorectomy for a high-grade,
Spraul CW, Grossniklaus HE, Giles JT. Müllerian Mixed Tumor Metastatic to the Iris and Ciliary Body. Arch Ophthalmol. 1997;115(1):122-123. doi:10.1001/archopht.1997.01100150124026