February 1997

Vitreous Substitutes

Author Affiliations

Madison, Wis


by Gholam A. Peyman, MD, and Joel A. Schulman, MD, 214 pp, $85, with illus, ISBN 0-8385-9484-0, East Nor-walk, Conn, Appleton & Lange, 1995.

Arch Ophthalmol. 1997;115(2):297. doi:10.1001/archopht.1997.01100150299041

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The removal of vitreous by surgical techniques was a great revolution in ophthalmic surgery. More recently, the development of vitreous substitutes has resulted in further advances. The publication of Drs Peyman and Schulman's small, though somewhat expensive, volume is particularly timely now that silicone oil, long-acting gases, and heavier-than-water perfluorocarbon liquids have been approved for clinical use by the Food and Drug Administration. There are but 3 chapters, each devoted to 1 of the vitreous substitute materials and each summarizing a wealth of basic science and clinical trial information as well as the techniques used for their surgical applications.

In the opening pages of the book, credit is appropriately given to Paul A. Cibus, MD, and Leland C. Clark, Jr, PhD, for their pioneering work in silicone oil use in the development of fluorocarbon liquids.

The silicone oil chapter devotes adequate attention to the complications of its use, ie, emulsification,

First Page Preview View Large
First page PDF preview
First page PDF preview