The accuracy of the clinical diagnosis of posterior uveal melanoma has steadily improved during the last several decades.1 Misdiagnosis at tertiary referral centers began to decline below 4% by the 1970s.2,3 In 1990, the proportion of misdiagnosed choroidal melanomas in the Collaborative Ocular Melanoma Study (COMS) was 0.48%, the lowest ever reported.4 The results of the COMS were so good that the study group concluded "the major challenge with regard to posterior melanoma is no longer that of correct diagnosis but rather determination of the optimal treatment."4 It is uncertain how generalizable these specific results are to the community practice of ocular oncology.
A survey was conducted at the University of South Florida, Tampa, to compare the accuracy of diagnosing posterior uveal melanoma in Florida with that reported in the COMS. During the 48 months from June 1, 1992, through May 31, 1996, 53 patients had
Margo CE. The Accuracy of Diagnosis of Posterior Uveal Melanoma. Arch Ophthalmol. 1997;115(3):432-433. doi:10.1001/archopht.1997.01100150434028