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May 1997

Bilateral Candida parapsilosis Endophthalmitis

Author Affiliations

From the Retina Service (Drs Wong and Tasman) and Department of Pathology (Dr Eagle), Wills Eye Hospital, Philadelphia, Pa; and Fundacion Oftalmologica Nacional, Bogotá, Colombia (Dr Rodriguez). Dr Wong is currently in private practice in Honolulu, Hawaii. None of the authors have proprietary interest in the development or marketing of any drug or device used in this study.

Arch Ophthalmol. 1997;115(5):670-672. doi:10.1001/archopht.1997.01100150672022

We describe a patient with bilateral, delayed endophthalmitis who underwent bilateral pars plana vitrectomy, total capsulectomy, intraocular lens exchange, intravitreal injection of amphotericin B, and oral fluconazole therapy. The long-term inflammation resolved, and vitreous cultures from both eyes yielded Candida parapsilosis. Histopathologic examination revealed sequestered yeast forms in the capsular bags.