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August 1997

Unifocal Helioid Choroiditis

Author Affiliations

From the Department of Ophthalmology, Northwestern University Medical School, Chicago, Ill.

Arch Ophthalmol. 1997;115(8):1007-1013. doi:10.1001/archopht.1997.01100160177006

Objective:  To report a previously undescribed clinical entity involving an unusual inflammatory lesion of the choroid.

Patients:  Six young, healthy patients experienced acute unilateral visual loss secondary to unifocal choroiditis in the macula.

Results:  All patients exhibited a solitary, elevated, yellow-white active focus of choroiditis with overlying subretinal fluid and in some cases subretinal hemorrhaging. The lesions were approximately 1 disc diameter in size and, on follow-up, showed minimal growth, then gradual resolution of the subretinal fluid. No other signs of ocular inflammation were noted, except in 1 patient who had anterior chamber and vitreous inflammation. In the 3 patients with prolonged follow-up, elevated white plaquelike lesions persisted with little change over time. Relapses were seen, and some permanent visual loss occurred in 1 of the 3 patients. Systemic evaluations revealed no definitive etiology.

Conclusions:  To our knowledge, these patients exhibit an undescribed clinical entity, separable from previously established choroidal disorders. The cause of the lesions remains uncertain. We call this entity "unifocal helioid choroiditis."