Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
In the Small Case Series article titled “Novel Mutation in BEST1 Associated With Retinoschisis,” published online on April 9, 2013, and in the June 2013 issue of JAMA Ophthalmology (2013;131:794-798. doi:10.1001/jamaophthalmol.2013.2047), a phenotypically significant polymorphism in the initial sequencing of the BEST1 gene was identified: (Glu213Lys). However, a second potentially phenotypically significant mutation (Pro404 del1cctC) was omitted. Thus, the sentences, “In our siblings, 5 separate polymorphisms were identified in sequencing BEST1. Only 1 of these was deemed phenotypically significant: a single guanine to adenosine substitution resulting in a Glu213Lys amino acid change.” should have read as, “In our siblings, 6 separate polymorphisms were identified in sequencing BEST1. Only 2 of these were deemed phenotypically significant: a single guanine to adenosine substitution resulting in a Glu213Lys amino acid change and a frameshift mutation at amino acid position 404 (Pro404 del1cctC).” This article was corrected online.
Omitted Mutation. JAMA Ophthalmol. 2013;131(9):1249. doi:10.1001/jamaophthalmol.2013.5755