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Article
April 1968

IRRIGATION OF ANTERIOR CHAMBER WITH NEOMYCIN-POLYMYXIN SOLUTION IN INTRAOCULAR SURGERY

Author Affiliations

Eye Foundation Hospital Birmingham, Ala

Arch Ophthalmol. 1968;79(4):506. doi:10.1001/archopht.1968.03850040508027

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Abstract

To the Editor.  —In an effort to minimize the risk of the occurrence of postoperative infection, the anterior chamber has been routinely irrigated with a solution of neomycin and polymyxin after intraocular surgery. Thus far, we have accumulated more than 250 cases from January 1966 through January 1968 with no signs of postoperative infection. We plan to extend this series over a period of years in an attempt to evaluate the efficacy of this form of prophylaxis. To the best of our knowledge, there are no reports of anterior chamber irrigation with antibiotics after intraocular surgery.The solution employed is mixed in the following proportions: 0.5 gm neomycin and 100 mg polymyxin B/100 cc solution. The solution is autoclaved prior to use. In routine cataract extraction ¼ to ½ cc of the solution is used to irrigate the anterior chamber after lens delivery and prior to tying the sutures. A bulb

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