A polarographic technique for quantifying topographically the activity within and adjacent to an epithelial lesion is described. Control values for oxygen flux across the normal tear-epithelial interface, flux values across a standard wound interface, and the longitudinal healing course for such a wound, quantified polarographically, are given.
Hill RM, Keates RH. Quantifying Epithelial Healing of the Cornea in Vivo. Arch Ophthalmol. 1969;82(5):675-680. doi:10.1001/archopht.1969.00990020669016