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Article
January 1970

Fluorescein Angiography of Choroidal Melanomas

Author Affiliations

Los Angeles
From the departments of ophthalmology (Drs. Pettit, Christensen, and Barton) and pathology (Dr. Foos) and Jules Stein Eye Institute, UCLA School of Medicine, Los Angeles.

Arch Ophthalmol. 1970;83(1):27-38. doi:10.1001/archopht.1970.00990030029006
Abstract

Thirty-six patients with intraocular malignant melanomas were studied using fluorescein angiography. Of these, 86% demonstrated a pattern characterized by gradually increasing fluorescence which starts at or before the arterial phase, increases in intensity well into the recirculation phase, and persists for at least 45 minutes. Five of 36 melanomas studied did not conform to this pattern. Analysis of these five cases revealed that heavy pigmentation of the tumor and subretinal hemorrhage or exudate obscured the expected fluorescence. Fourteen patients with benign melanoma of the choroid, with and without drusen, were also studied by fluorescein angiography.

References
1.
Maclean, A.L., and Maumenee, A.E.:  Hemangioma of the Choroid , Amer J Ophthal 50:3-11 ( (July) ) 1960.
2.
Novotny, H.R., and Alvis, D.L.:  A Method of Photographing Fluorescence in Circulating Blood in the Human Retina , Circulation 24:82-86 ( (July) ) 1961.Article
3.
Ferrer, O.M.:  Serial Fluorescein Fundus Photography of Retinal Circulation , Amer J Ophthal 60:587-591 ( (Oct) ) 1965.
4.
Allen, L., et al:  Instant Positive Photographs and Stereograms of Ocular Fundus Fluorescence , Arch Ophthal 75:192-198 ( (Feb) ) 1966.Article
5.
Hodge, J.V., and Clemett, R.S.:  Improved Method of Fluorescence Angiography of the Retina , Amer J Ophthal 61:1400-1404 ( (June) ) 1966.
6.
Snyder, W.B., and Allen, L.:  Fluorescence Angiography of Ocular Tumors , Trans Amer Acad Ophthal Otolaryng 71:820-832 ( (Sept-Oct) ) 1967.
7.
Norton, E.W.D., et al:  Fluorescein Fundus Photography: An Aid in the Differential Diagnosis of Posterior Ocular Lesions , Trans Amer Acad Ophthal Otolaryng 68:755-765 ( (Sept-Oct) ) 1964.
8.
Rubinstein, K.:  Differential Diagnosis of Malignant Melanoma , Trans Ophthal Soc UK 87:447-456, 1967.
9.
Norton, E., and Gutman, F.:  Fluorescein Angiography and Hemangiomas of the Choroid , Arch Ophthal 78:121-125 ( (Aug) ) 1967.Article
10.
Gass, D.M.:  Pathogenesis of Disciform Detachment of the Neuroepithelium , Amer J Ophthal 63:645-660 ( (June) ) 1967.
11.
Shikano, S., and Shimizu, K.: Atlas of Fluorescence Fundus Angiography , Philadelphia: W. B. Saunders Co., 1968.
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