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Article
August 1971

Hydrophilic Contact Lenses in Corneal DiseaseIII. Topical Hypertonic Saline Therapy in Bullous Keratopathy

Author Affiliations

Boston
From the Department of Ophthalmology and the Massachusetts Lions Eye Research Laboratories, Boston University School of Medicine, Boston.

Arch Ophthalmol. 1971;86(2):133-137. doi:10.1001/archopht.1971.01000010135003
Abstract

Four patients suffering from chronic bullous keratopathy with minimal stromal scarring were fitted with a hydrophilic contact lens. The lens was worn continuously, 24 hours a day, and 5% sodium chloride drops were administered topically every two hours during the day. Two of the four patients experienced a satisfactory response to therapy manifested by decreased epithelial and stromal edema and improvement in visual acuity. Approximately two weeks of therapy were required before clinical improvement could be documented in successful cases. The rationale for employing this regimen and the physiological principles which determine therapeutic success or failure are discussed.

References
1.
Leibowitz HM, Rosenthal P:  Hydrophilic contact lenses in corneal disease: II. Bullous keratopathy . Arch Ophthal 85:283-285, 1971.Article
2.
Leibowitz HM, Rosenthal P:  Hydrophilic contact lenses in corneal disease: I. Superficial, sterile indolent ulcers . Arch Ophthal 85:163-166, 1971.Article
3.
Donn A, Miller SL, Mallett NM:  Water permeability of the living cornea . Arch Ophthal 70:515-521, 1963.Article
4.
Maurice DM:  The permeability of sodium ions of the living rabbit's cornea . J Physiol 112:367-391, 1951.
5.
Maurice DM:  The permeability of the cornea . Ophthal Lit 7:3-26, 1953.
6.
Brubaker RF, Kupfer C:  Microcryoscopic determination of the osmolality of interstitial fluid in the living rabbit cornea . Invest Ophthal 1:653-660, 1962.
7.
Stanley JA, Mishima S, Klyce SD Jr:  In vivo determination of endothelial permeability to water . Invest Ophthal 5:371-377, 1966.
8.
Cogan DG:  Some practical considerations pertaining to corneal edema . Arch Ophthal 25:552-556, 1941.Article
9.
Gassett AR, Kaufman HE:  Therapeutic uses of hydrophilic contact lenses . Amer J Ophthal 69:252-259, 1970.
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