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Article
January 1972

The Borderline Fluorescent Treponemal Antibody Absorption Test ReactorNeuro-ophthalmological Status

Author Affiliations

Miami, Fla
From the Department of Ophthalmology, University of Miami School of Medicine, Miami, Fla.

Arch Ophthalmol. 1972;87(1):16-20. doi:10.1001/archopht.1972.01000020018003
Abstract

A comparative study of 105 patients with borderline serum fluorescent treponemal antibody absorption (FTA-ABS) test results and 50 patients with nonreactive serum FTA-ABS test results was performed. "Syphilitic pupils" were found in 4% of the patients with nonreactive FTA-ABS tests, but in 15% of the borderline group. Optic atrophy was found in 18% of the control group and in 29% of the borderline group. Optic neuritis was present in 2% of the control group, and in 9.5% of the borderline group. The report of a ± nonreactive or borderline FTA-ABS test is significant to the clinician. Not only should the test be repeated, but a careful history should be taken and a complete examination for subtle signs of late ocular and neurosyphilis should be performed.

References
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Harner RE, Smith JL, Israel CW:  The FTA-ABS test in late syphilis . JAMA 203:545, 1968.Article
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Diem K (ed):  Scientific tables , in Documenta Geigy , ed 6. Ardsley, NY, Geigy, 1968.
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Cohen P, Stout G, Ende N:  Serologic reactivity in consecutive patients admitted to a general hospital . Arch Intern Med 124:364, 1969.Article
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Smith JL: Spirochetes in Late Seronegative Syphilis, Penicillin Notwithstanding . Springfield, Ill, Charles C Thomas Publisher, 1969, p 331.
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