[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
February 1975

Invasive Squamous Cell Carcinoma of the Conjunctiva

Author Affiliations

From the Eye Pathology Laboratory, The Wilmer Institute, and the Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore.

Arch Ophthalmol. 1975;93(2):119-122. doi:10.1001/archopht.1975.01010020125005

In 27 cases of invasive conjunctival squamous cell carcinoma, three cases of deep corneal invasion and two cases of intraocular extension were found. Four cases showed orbital invasion, and one patient died of generalized metastases 18 months after diagnosis. The relatively low-grade nature of these lesions and their potential for local treatment is noted, but it is emphasized that careful clinical examination and close cooperation with the pathologist to ensure adequate evaluation of excised tissue are essential.

Zimmerman LE:  The Poklington memorial lecture: The cancerous, precancerous and pseudocancerous lesions of the cornea and conjunctiva , in Rycroft PV (ed): Corneo-Plastic Surgery . New York, Pergamon Press, 1969, pp 547-555.
François J, Hanssens M, Germen M:  Épithéliomas perforants du limbe et de la conjonctive bulbaire . Ann Oculist 200:505-521, 1967.
Greer CH:  Limbal epithelioma with intraocular invasion . Br J Ophthalmol 46:306-307, 1962.Article
Stokes JJ:  Intraocular extension of epibulbar squamous cell carcinoma of the limbus . Trans Am Acad Ophthalmol Otolaryngol 59:143-146, 1955.
Dollfus MA:  Un cas d'épithélioma perforant du limbe et considérations cliniques et thérapeutiques sur les épithéliomas de la conjonctive bulbaire observés depuis 30 ans à la Fondation Curie à Paris . Bull Soc Belge Ophthalmol 146:295-301, 1967.
Duke-Elder S: System of Ophthalmology . London, Henry Kimpton, 1965, vol 8, pp 1165-1175.
Irvine AR Jr:  Dyskeratotic epibulbar tumors . Trans Am Ophthalmol Soc 61:243-273, 1963.
Zimmerman LE:  Squamous cell carcinoma and related lesions of the bulbar conjunctiva , in Boniuk M (ed): Ocular and Adnexal Tumors . St. Louis, CV Mosby, 1964, pp 49-74.