[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
December 1975

Retinal Ischemia in Diabetic Retinopathy

Author Affiliations

From the Department of Ophthalmology, University of Wisconsin School of Medicine, Madison.

Arch Ophthalmol. 1975;93(12):1300-1310. doi:10.1001/archopht.1975.01010020934002

• Eight patients with proliferative diabetic retinopathy developed extensive retinal arteriolar and capillary obstruction. Ophthalmoscopy showed many white, thread-like retinal arterioles associated with capillary and venous dilatation. Widespread retinal arteriolar and capillary nonperfusion was demonstrated by fluorescein angiography. Ischemic maculopathy resulted in severe loss of visual acuity in some eyes. The severe degree of retinal ischemia was accompanied by optic disc pallor and neovascularization and a high incidence of rubeosis iridis with neovascular glaucoma. Patients with this variety of diabetic retinopathy have a poor prognosis of retaining useful vision.

Ashton N:  Arteriolar involvement in diabetic retinopathy . Br J Ophthalmol 37:282-292, 1953.Article
Cogan DG, Toussaint D, Kuwabara T:  Retinal vascular patterns: IV. Diabetic retinopathy . Arch Ophthalmol 66:366-378, 1961.Article
Bloodworth JMB:  Diabetic retinopathy . Diabetes 11:1-22, 1962.
Ashton N:  Studies of the retinal capillaries in relation to diabetic and other retinopathies . Br J Ophthalmol 47:521-538, 1963.Article
Scott DJ, Dollery CT, Hill DW, et al:  Fluorescein studies of diabetic retinopathy . Br Med J 1:811-814, 1964.Article
Kohner EM, Dollery CT, Paterson JW, et al:  Arterial fluorescein studies in diabetic retinopathy . Diabetes 16:1-10, 1967.
Oosterhuis JA, Vink R:  Fluorescein photography in diabetic retinopathy , in Henkes H (ed): Perspectives in Ophthalmology . Rotterdam, Excerpta Medica Foundation, 1968, pp 115-132.
Smith JL:  Unilateral glaucoma in carotid occlusive disease . JAMA 182:683-684, 1962.Article
Ostler HB:  Pulseless disease . Am J Ophthalmol 43:583-589, 1957.
Aiello LM, Beetham WP, Balodimos MC, et al:  Ruby laser photocoagulation in treatment of diabetic proliferating retinopathy , in Goldberg MF, Fine SL (eds): Symposium on the Treatment of Diabetic Retinopathy . Public Health Service Publication No. 1890, 1968, pp 437-463.
Bresnick GH, de Venecia G, Myers FL, et al: Perifoveal capillary closure in diabetic retinopathy, to be published.
Speakman JS, Mortimer CB, Briant TDR, et al:  Pituitary ablation for diabetic retinopathy . Canad Med Ass J 94:627-635, 1966.
Balodimos MC, Aiello LM, Koncz L, et al:  Fluorescein angiography in diabetic retinopathy , in Almaric P (ed): Proceedings of the International Symposium on Fluorescein Angiography, Albi, 1969 . Basel, S Karger, 1971, p 391.