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August 1977

Tonography and Projection PerimetryRelationship According to Receiver Operating Characteristic Curves

Author Affiliations

Marijane Krohn
From the Department of Ophthalmology, University of California, Davis, Calif.

Arch Ophthalmol. 1977;95(8):1353-1356. doi:10.1001/archopht.1977.04450080063002

• Previous large scale tonographic studies revealed a significant overlap of coefficient of outflow (C) values for normal and glaucomatous eyes, but their differential diagnosis rested primarily on tangent screen visual field tests. To determine whether projection perimetry would make a difference in the correlation of outflow coefficients with glaucoma, 434 eyes from normal, ocular hypertensive (those without scotomas but with elevated intraocular pressure) and glaucomatous categories were evaluated. Results support the conclusions of earlier work concerning C value overlap and demonstrate the relatively better specificity of the initial Intraocular pressure over one coefficient of outflow (Po/C) in distinguishing normal from glaucomatous eyes. It also shows that ocular hypertensives as a group are no different from glaucoma patients with regard to their aqueous outflow. Tonographic tests are, therefore, useful in identifying those eyes that need to be watched closely for the development of glaucomatous change.

(Arch Ophthalmol 95:1353-1356, 1977)

Grant WM:  Tonographic method for measuring the facility and rate of aqueous flow in human eyes . Arch Ophthalmol 44:204-214, 1950.Article
Grant WM:  Clinical measurements of aqueous outflow . Arch Ophthalmol 46:113-131, 1951.Article
Kronfeld PC:  Tonography . Arch Ophthalmol 48:393-404, 1952.Article
de Roetth A, Knighton WS:  Clinical evaluation of the aqueous-flow test . Arch Ophthalmol 48:148-153, 1952.Article
Becker B:  Tonography in the diagnosis of simple (open angle) glaucoma . Trans Am Acad Ophthalmol Otolaryngol 65:156-162, 1961.
Becker B, Christensen RE:  Water drinking and tonography in the diagnosis of glaucoma . Arch Ophthalmol 56:321-326, 1956.Article
Roberts RW:  Tonography in the management of glaucoma . Trans Am Acad Ophthalmol Otolaryngol 65:163-170, 1961.
de Roetth A:  Clinical evaluation of tonography . Am J Ophthalmol 59:169-179, 1965.
Podos SM, Becker B:  Tonography—current thoughts . Am J Ophthalmol 75:733-735, 1973.
Drance SM:  Medical management of early chronic open angle glaucoma , in: Symposium on Glaucoma: Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1975, pp 68-80.
Goldmann H:  An analysis of some concepts concerning chronic simple glaucoma . Am J Ophthalmol 80:409-416, 1975.
Portney GL: Glaucoma Guidebook . Philadelphia, Lea & Febiger, 1977, pp 87-106.
McNeil BJ, Keller E, Adelstein SJ:  Primer on certain elements of medical decision making . N Engl J Med 293:211-215, 1975.Article
Armaly MF:  Ocular pressure and visual fields . Arch Ophthalmol 81:25-40, 1969.Article
Wilensky JT, Podos SM, Becker B:  Prognostic indicators in ocular hypertension . Arch Ophthalmol 91:200-202, 1974.Article
Kass MA, Kolker AE, Becker B:  Prognostic factors in glaucomatous visual field loss . Arch Ophthalmol 94:1274-1276, 1976.Article