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Article
April 1978

Metastatic Coccidioidal Endophthalmitis

Author Affiliations

From the Departments of Ophthalmology (Drs Cutler and Paul) and Pulmonary Medicine (Dr Beamis), Naval Regional Medical Center; and Section of Ophthalmology (Dr Binder), Veterans Administration Hospital, San Diego.

Arch Ophthalmol. 1978;96(4):689-691. doi:10.1001/archopht.1978.03910050379016
Abstract

• A severe granulomatous iridocyclitis developed in association with a cavitary pulmonary lesion in a 29-year-old man. The initial diagnosis and treatment was for pulmonary tuberculosis with tuberculous uveitis. Although the pulmonary lesion improved with antituberculous therapy, the condition of the eye deteriorated. An anterior-chamber tap was positive for Coccidioides immitis, and the patient was treated with intravenous and two intracameral injections of amphotericin B. The eye was ultimately enucleated three weeks after the initial intracameral injection, and yet was culture-positive for the organism. Histopathologic examination disclosed diffuse involvement of the anterior segment, with multiple spherules present within the iris and limbus.

References
1.
Wilson JW, Plunkett OA: The Fungus Diseases of Man . Los Angeles, University of California Press, 1965, pp 25-48.
2.
Levitt JM:  Ocular manifestations in coccidioidomycosis . Am J Ophthalmol 31:1626, 1948.
3.
Lovekin L:  Coccidioidomycosis: Report of a case with intraocular involvement . Am J Ophthalmol 34:621-623, 1951.
4.
Brown WC, Hudson KE, Nisbet AA:  Pulmonary coccidioidomycosis associated with Jensen's disease . Am J Ophthalmol 43:965-967, 1957.
5.
Brown WC, Kellenberger RE, Hudson KE:  Granulomatous uveitis associated with disseminated coccidioidomycosis . Am J Ophthalmol 45:102-104, 1958.
6.
Pettit TH, Learn RN, Foos RY:  Intraocular coccidioidomycosis . Arch Ophthalmol 77:655-661, 1967.Article
7.
Hagele AJ, Evans DJ, Larwood TR:  Primary Endophthalmic coccidioidomycosis: Report of a case of exogenous, primary coccidioidomycosis of the eye diagnosed prior to enucleation , in Ajello L (ed): Second Symposium of Coccidioidomycosis . Tucson, University of Arizona Press, 1967, pp 37-39.
8.
Boyden BS, Yee DS:  Bilateral coccidioidal choroiditis: A clinicopathologic case report . Trans Am Acad Ophthalmol Otolaryngol , 76( (3) ):1006-1010, 1971.
9.
Olavarria R, Fajardo LF:  Ophthalmic coccidioidomycosis: Case report and review . Arch Pathol 92:191-195, 1971.
10.
Rainin EA, Little HL:  Ocular coccidioidomycosis: A clinicopathologic case report . Trans Am Acad Ophthalmol Otolaryngol 76( (3) ):645-651, 1972.
11.
Bell L, Font RL:  Granulomatous anterior uveitis caused by Coccidioides immitis . Am J Ophthalmol 74:93-98, 1972.
12.
Chandler JW, Kalina RE, Milam DF:  Coccidioidal choroiditis following renal transplantation . Am J Ophthalmol 74:1080-1085, 1972.
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