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November 1978

Endothelial Changes in Rabbit CorneasObservation by Specular Microscopy During Storage in McCarey-Kaufman (M-K) Medium

Author Affiliations

From the Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

Arch Ophthalmol. 1978;96(11):2108-2110. doi:10.1001/archopht.1978.03910060488021

• Corneal banks are beginning to screen donor tissue with a specular microscope to detect abnormal endothelium. To determine the appearance of normal corneal endothelium under storage conditions, the endothelium of healthy rabbit corneas was examined with a modified specular microscope while being stored in McCarey-Kaufman (M-K) medium at 4 °C. Black areas within endothelial cells and decreased clarity of the endothelial cell borders were observed during storage and were found to be reversible on warming of the M-K medium.

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