[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.209.213. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 1979

Visual Resolution in a Patient Exhibiting a Visual Fatigue or Saturation-like EffectProbable Multiple Sclerosis

Author Affiliations

From the Department of Ophthalmology and the Center for Sensory Studies, University of Florida College of Medicine, Gainesville.

Arch Ophthalmol. 1979;97(1):76-78. doi:10.1001/archopht.1979.01020010016003
Abstract

• A rapid visual resolution test conducted on available equipment reveals the presence of rapid falloff in acuity in a case of probable multiple sclerosis. Intense large field illumination was used, and grating acuity was tested using laser red light. The effect is so large that minor anomalies (not subjectively appreciated) or the residuum of earlier minor attacks of retrobulbar optic neuritis can be readily detected. A related "visual fatigue or saturation-like syndrome" was described earlier.

In bright environments these patients' vision fades. Briefly closing the eyes restores visual sensitivity. Providing filters or lowering the light level tends to maintain vision.

This test must be studied intensively. It offers a noninvasive simple means of showing underlying anomalies in neural conduction of the visual signal. Such anomalies can be prognostic and previously have been revealed only with sophisticated electrophysiological techniques.

References
1.
Galvin RJ, Regan D, Heron JR:  A possible means of monitoring the progress of demyelination in multiple sclerosis: Effect of body temperature on visual perception of double light flashes . J Neurol Neurosurg Psychiatry 39:861-865, 1976.Article
2.
Hennerici M, Wenzel D, Freund HJ:  The comparison of small-size rectangle and checker board stimulation for the evaluation of delayed visual evoked responses in patients suspected of multiple sclerosis . Brain 100:119-136, 1977.Article
3.
Enoch JH, Sunga R:  Development of quantitative perimetric tests . Doc Ophthalmol 26:215-229, 1969.Article
4.
Enoch JM, Berger R, Birns R:  A static perimetric technique believed to test receptive field properties: Extension and verification of the analysis . Doc Ophthalmol 29:127-153, 1970.Article
5.
Sunga R, Enoch JM:  Further perimetric analysis of patients with lesions of the visual pathways . Am J Ophthalmol 70:403-422, 1970.
6.
Zappia RJ, Enoch JM, Stamper R, et al:  The Riddoch phenomenon revealed in nonoccipital lesions . Br J Ophthalmol 55:416-420, 1971.Article
7.
Enoch JM, Lawrence B:  A perimetric technique believed to test receptive field properties: Sequential evaluation in glaucoma and other conditions . Am J Ophthalmol 80:734-758, 1975.
8.
Campos EC: Perimetria statica con flash ripetuti nel tempo sec. Enoch: un semplice metodo per la valutazione di pazienti neuro-oftalmologici. Boll d'Ocul, to be published.
9.
Regan D, Silver R, Murray TJ: Visual acuity and contrast in multiple sclerosis: Hidden visual loss. Brain, to be published.
10.
Enoch JM:  Quantitative layer-by-layer perimetry: Proctor Lecture of the Association for Research in Vision and Ophthalmology 1977 . Invest Ophthalmol 17:199-257, 1978.
11.
Enoch JM, Campos EC, Greer M, et al:  Measurement of visual resolution at high luminance levels in patients with possible demyelinating disease , in Proceedings of the First International Ophthalmological Optics Symposium, Tokyo, Japan, May 8-9,1978 . International Ophthalmological Optics Congress, 1978.
×