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February 1982

Graves' Ophthalmopathy Evaluated by Infrared Eye-Movement Recordings

Author Affiliations

From the Eye Movement Laboratory, Estelle Doheny Eye Foundation, Los Angeles; and the Departments of Ophthalmology and Neurosurgery, University of Southern California, Los Angeles. Dr Unsöld is now with Universitats-Augenklinik, Freiburg, West Germany.

Arch Ophthalmol. 1982;100(2):324-328. doi:10.1001/archopht.1982.01030030326022

• Thirteen patients with varying degrees of Graves' ophthalmopathy were examined using high-resolution infrared oculography to determine peak velocities for horizontal eye movements between 3° and 30°. As severity of the orbital disease increased, peak velocities became substantially lower. Vertical-muscle surgery failed to have any effect on peak velocity of horizontal eye movements. In contrast, orbital decompression caused notable improvement in peak velocity of eye movements. Eye-movement recordings, which provide a measure of extraocular muscle function rather than structure, may provide a safe, sensitive, and accurate method for classifying and following up patients with Graves' ophthalmopathy.

Coleman DJ, Jack RL, Franzen LA, et al:  High resolution B-scan ultrasonography of the orbit: V. Eye changes of Graves' disease . Arch Ophthalmol 1972;88:465-471.Article
Shammas HJF, Minckler DS, Ogden C:  Ultrasound in early thyroid orbitopathy . Arch Ophthalmol 1980;98:277-279.Article
Ossoinig KC:  A-scan echography and orbital disease . Mod Probl Ophthalmol 1978;14:1199-1209.
Trokel SL, Hilal SK:  Recognition and differential diagnosis of enlarged extraocular muscles in computed tomography . Am J Ophthalmol 1979;87:503-512.
Inoue Y, Inoue T, Ichikizaki K, et al:  Computerized orbital tomography in dysthyroid ophthalmopathy . Jpn J Ophthalmol 1978;22:286-296.
Inoue Y, Inoue T, Ichikizaki K, et al:  The role of extraocular muscle in the development of dysthyroid ophthalmopathy . Jpn J Clin Ophthalmol 1978;32:901-905.
Hanna C:  Cataract of toxic etiology , in Bellows JG (ed): Cataract and Abnormalities of the Lens . New York, Grune & Stratton Inc, 1975, pp 217-224.
Rosenbaum AL, Metz HS, Carlson M, et al:  Adjustable rectus muscle recession surgery: A follow-up study . Arch Ophthalmol 1977;95:817-820.Article
Long JC, Ellis GD:  Temporal decompression of the orbit for thyroid exophthalmos . Am J Ophthalmol 1966;62:1089-1098.
Walsh TE, Ogura JH:  Transantral orbital decompression for malignant exophthalmos . Laryngoscope 1957;67:544-568.Article
Naffziger HC:  Pathologic changes in the orbit in progressive exophthalmos with special reference to alterations in the extra-ocular muscles and the optic disks . Arch Ophthalmol 1933;9:1-12.Article
Rundle FF, Pochin EE:  The orbital tissues in thyrotoxicosis: Quantitative analysis of the orbital tissues . Clin Sci 1944;5:51-74.
Katz B:  The relation between force and speed in muscular contraction . J Physiol 1939;96:45-64.
Hsu FK, Bahill AT, Stark L:  Parametric sensitivity analysis of a homeomorphic model for saccadic and vergence eye movements . Comput Programs Biomed 1976;6:108-116.Article
Lehman S, Stark L:  Simulation of linear and non-linear eye movement models: Sensitivity analyses and enumeration studies of time optimal control . J Cybern Inform Sci 1979;3:21-43.
Metz HS:  Saccadic velocity studies in patients with endocrine ocular disease . Am J Ophthalmol 1977;84:695-699.