[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.209.213. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
November 1982

Combined Ocular Infection With Cytomegalovirus and Cryptococcosis

Author Affiliations

From the Department of Ophthalmology, University of Pittsburgh School of Medicine, Eye and Ear Hospital (Dr Doft); and the Bascom Palmer Eye Institute, University of Miami School of Medicine (Dr Curtin).

Arch Ophthalmol. 1982;100(11):1800-1803. doi:10.1001/archopht.1982.01030040780014
Abstract

• To our knowledge, this is the first published description of the clinical and pathologic features of combined ocular infection with both cytomegalovirus and Cryptococcus. Infection occurred in a patient treated by immunosuppression and corticosteroid therapy. This article emphasizes that ocular findings may be the first sign of disseminated opportunistic infection and that clinical manifestations may be sufficient to allow accurate diagnosis of opportunistic retinitis.

References
1.
Cogan DG:  Immunosuppression and eye disease: First Vail lecture . Am J Ophthalmol 1977;83:777-788.
2.
Levin MJ, Zaia JA:  Immunosuppression and Infection—progress? N Engl J Med 1977;296:1406-1408.Article
3.
Khodadoust AA, Payne JW:  Cryptococcal (torular) retinitis: A clinicopathologic case report . Am J Ophthalmol 1969;67:745-750.
4.
Williams DM, Krick JA, Remington JS:  Pulmonary infection in the compromised host: Part I . Am Rev Respir Dis 1976;114:359-394.
5.
Glasgow LA:  Cellular immunity in host resistance to viral infections . Arch Intern Med 1970;126:125-133.Article
6.
Rowe WP, Hartley JW, Waterman S, et al:  Cytopathogenic agent resembling human salivary gland virus recovered from tissue cultures of human adenoids . Proc Soc Exp Biol Med 1956;92:418-424.Article
7.
Murray HW, Knox DL, Green WR, et al:  Cytomegalovirus retinitis in adults: A manifestation of disseminated viral infection . Am J Med 1977;63:574-584.Article
8.
De Venecia G, Zu Rhein GM, Pratt MV, et al:  Cytomegalic inclusion retinitis: A clinical, histopathologic, and ultrastructural study . Arch Ophthalmol 1971;86:44-57.Article
9.
Meredith TA, Aaberg TM, Reeser FH:  Rhegmatogenous retinal detachment complicating cytomegalovirus retinitis . Am J Ophthalmol 1979;87:793-796.
10.
Chumbley LC, Robertson DM, Smith TF, et al:  Adult cytomegalovirus inclusion retino-uveitis . Am J Ophthalmol 1975;80:807-816.
11.
Aaberg TM, Cesarz TJ, Rytel MW:  Correlation of virology and clinical course of cytomegalovirus retinitis . Am J Ophthalmol 1972;74:407-415.
12.
Cox F, Meyer D, Hughes WT:  Cytomegalovirus in tears from patients with normal eyes and with acute cytomegalovirus chorioretinitis . Am J Ophthalmol 1975;80:817-824.
13.
Rytel MW, Aaberg TM, Dee TH, et al:  Therapy of cytomegalovirus retinitis with transfer factor . Cell Immunol 1975;19:8-21.Article
14.
Pollard RB, Egbert PR, Gallagher JG, et al:  Cytomegalovirus retinitis in immunosuppressed hosts: I. Natural history and effects of treatment with adenine arabinoside . Ann Intern Med 1980;93:655-664.Article
15.
Okun E, Butler WT:  Ophthalmologic complications of cryptococcal meningitis . Arch Ophthalmol 1964;71:52-57.Article
16.
Lesser RL, Simon RM, Leon H, et al:  Cryptococcal meningitis and internal ophthalmoplegia . Am J Ophthalmol 1979;87:682-687.
17.
Kupfer C, McCrane E:  A possible cause of decreased vision in cryptococcal meningitis . Invest Ophthalmol Vis Sci 1974;13:801-804.
18.
Gonyea EF, Heilman KM:  Neuro-ophthalmic aspects of central nervous system cryptococcosis: Internuclear and supranuclear ophthalmoplegia . Arch Ophthalmol 1972;87:164-168.Article
19.
Shields JA, Wright DM, Augsburger JJ, et al:  Cryptococcal chorioretinitis . Am J Ophthalmol 1980;89:210-218.
20.
Hiles DA, Font RL:  Bilateral intraocular cryptococcosis with unilateral spontaneous regression: Report of a case and review of the literature . Am J Ophthalmol 1968;65:98-108.
21.
Avendano J, Tanishima T, Kuwabara T:  Ocular cryptococcosis . Am J Ophthalmol 1978;86:110-113.
22.
Foos RY: Ocular Complications of Hodgkin's Disease, UCLA No. A-4627. Read before the Verhoeff Society, Washington, DC, April 22, 1968.
23.
Egbert PR, Pollard RB, Gallagher JG, et al:  Cytomegalovirus retinitis in immunosuppressed hosts: II. Ocular manifestations . Ann Intern Med 1980;94:664-670.Article
×