[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
January 1983

Treatment of Contact Lenses With PapainIncrease in Wearing Time in Keratoconic Patients With Papillary Conjunctivitis

Author Affiliations

From the Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago (Dr Greiner); the Department of Cornea Research, Eye Research Institute of Retina Foundation (Drs Greiner and Allansmith), and the Department of Ophthalmology, Harvard Medical School (Dr Allansmith), Boston. Drs Korb and Finnemore are in private practice in Boston.

Arch Ophthalmol. 1983;101(1):48-50. doi:10.1001/archopht.1983.01040010050006

• In 15 Keratoconic patients with papillary conjunctivitis associated with wearing rigid polymethylmethacrylate contact lenses, the cleaning of the lenses with enzymatic contact lens cleaner (papain) increased lens wearing time in nine and diminished the symptoms of mucus and itching in 12. In 13 control, lens-wearing keratoconic subjects with papillary conjunctivitis, three had a decrease, four had an increase, and six had no change in lens wearing time and one had a diminution of symptoms. Use of the enzymatic contact lens cleaner did not, however, influence the biomicroscopic appearance of the papillary conjunctivitis. The inclusion of the enzymatic contact lens cleaner in the cleaning regimen offered an adequate improvement in wearing time and tolerance for three of four patients that previously suffered a reduction in wearing time that compromised or precluded their vocational responsibilities.

Korb DR, Allansmith MR, Greiner JV, et al:  Prevalence of conjunctival changes in wearers of hard contact lenses . Am J Ophthalmol 1980; 90:336-341.
Allansmith MR, Korb DR, Greiner JV, et al:  Giant papillary conjunctivitis in contact lens wearers . Am J Ophthalmol 1977;83:697-708.
Korb DR, Allansmith MR, Greiner JV, et al:  Biomicroscopic appearance of the conjunctiva in patients with papillary conjunctivitis associated with hard contact lens wear . Ophthalmology 1981;88:1132-1136.Article
Lowther GE, Hilbert JA:  Deposits on hydrophilic lenses: Differential appearance and clinical cases . Am J Optom Physiol Opt 1975;152:687-692.Article
Fowler SA, Greiner JV, Allansmith MR:  Soft contact lenses from patients with giant papillary conjunctivitis . Am J Ophthalmol 1979; 88:1056-1061.
Greiner JV, Henriquez AS, Weidman TA, et al:  'Second' mucus secretory system of the human conjunctiva . Invest Ophthalmol Vis Sci 1979; 18:123.
Greiner JV, Kenyon KR, Henriquez AS, et al:  Mucus secretory vesicles in conjunctival epithelial cells of contact lens wearers . Arch Ophthalmol 1980;98:1843-1846.Article
Greiner JV, Allansmith MR:  Effect of contact lens wear on the conjunctival mucus system . Ophthalmology 1981;88:821-832.Article
Allansmith MR, Baird RS, Greiner JV:  Density of goblet cells in vernal conjunctivitis and contact lens associated giant papillary conjunctivitis . Arch Ophthalmol 1981;99:884-885.Article