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February 1984

Bacterial Endophthalmitis After Closed Vitrectomy

Author Affiliations

From the Eye Research Institute of Retina Foundation; Massachusetts Eye and Ear Infirmary, Harvard Medical School; and Retina Associates, Boston.

Arch Ophthalmol. 1984;102(2):207-210. doi:10.1001/archopht.1984.01040030157016

• Four cases of bacterial endophthalmitis occurred after more than 2,800 closed vitrectomies. Despite vigorous antibiotic therapy, all four eyes were lost. The poor outcome seems to result from difficulties in diagnosing this condition in its early stages. Important clinical indications, such as orbital pain, corneal edema and infiltrate, excessive intraocular inflammatory reaction, hypopyon, and diminished fundus reflex, are often masked by the usual postoperative course. According to our study, the incidence of endophthalmitis after closed vitreous surgery is 0.14%. Three of the four patients with endophthalmitis were diabetic. Our clinical findings are compared with those in the four other cases reported in the literature.

Ghartey KN, Tolentino FI, Freeman HM, et al:  Closed vitreous surgery: XVII. Results and complications of pars plana vitrectomy . Arch Ophthalmol 1980;98:1248-1252.Article
Tolentino FI, Freeman HM, Tolentino FL:  Closed vitrectomy in the management of diabetic traction retinal detachment . Ophthalmology 1980;87:1078-1089.Article
Michels RG, Ryan SJ Jr:  Results and complications of 100 consecutive cases of pars plana vitrectomy . Am J Ophthalmol 1975;80:24-29.
Peyman GA, Huamonte FU, Goldberg MF, et al:  Four hundred consecutive pars plana vitrectomies with the vitrophage . Arch Ophthalmol 1978;96:45-50.Article
Syrdalen P:  One hundred consecutive cases of pars plana vitrectomy with the vitreous stripper . Acta Ophthalmol 1979;57:1039-1047.Article
May DR, Peyman GA:  Endophthalmitis after vitrectomy . Am J Ophthalmol 1976;81:520-523.
Blankenship GW:  Endophthalmitis after pars plana vitrectomy . Am J Ophthalmol 1977; 84:815-817.
Machemer R:  Special problems of the diabetic eye after vitrectomy , in: Symposium on Retinal Diseases, Transactions of the New Orleans Academy of Ophthalmology . St Louis, CV Mosby Co, 1977, pp 165-169.
Peyman GA, Paque JT, Meisels HI, et al:  Postoperative endophthalmitis: A comparison of methods for treatment and prophylaxis with gentamicin . Ophthalmic Surg 1975;6:45-55.
Forster RK, Abbott RL, Gelender H:  Management of infectious endophthalmitis . Ophthal- 1980;87:313-319.Article