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Article
May 1984

Chemical Preparation of the Eye in Ophthalmic SurgeryIII. Effect of Povidone-Iodine on the Conjunctiva

Author Affiliations

From the Departments of Ophthalmology (Drs Apt, Isenberg, and Paez) and Pathology (Dr Yoshimori), Jules Stein Eye Institute and Harbor-UCLA Medical Center, UCLA School of Medicine.

Arch Ophthalmol. 1984;102(5):728-729. doi:10.1001/archopht.1984.01040030584025
Abstract

• A half-strength povidone-iodine (Betadine) solution was used topically as part of the preoperative chemical preparation of the eye. Aerobic and anaerobic bacterial cultures of the conjunctiva were taken before and after the chemical preparation in 30 consecutive patients; the second eye served as a control. In the control eyes, no significant change in the number of colonies or species of bacteria was found. In the povidone-iodine-treated eyes, the numbers of colonies decreased 91% and the number of species decreased 50% (statistically significant). We therefore recommend that a halfstrength povidone-iodine solution be used as part of the chemical preparation of the eye for surgery.

References
1.
Apt L, Isenberg S:  Chemical preparation of skin and eye in ophthalmic surgery: An international survery . Ophthalmic Surg 1982;13:1026-1029.
2.
Isenberg S, Apt L, Yoshimori R:  Chemical preparation of the eye in ophthalmic surgery: I. Effect of conjunctival irrigation . Arch Ophthalmol 1983;101:761-763.Article
3.
Isenberg S, Apt L, Yoshimori R:  Chemical preparation of the eye in ophthalmic surgery: II. Effectiveness of mild silver protein solution . Arch Ophthalmol 1983;101:764-765.Article
4.
Saggers BA, Stewart GT:  Polyvinylpyrrolidone-iodine: An assessment of antibacterial activity . J Hyg 1964;62:509-518.Article
5.
Connel JF, Rousselot LM:  Povidone-iodine: Extensive surgical evaluation of a new antiseptic agent . Am J Surg 1964;108:849-855.Article
6.
Close AS, Stengel BF, Love HH, et al:  Preoperative skin preparation with povidone-iodine . Am J Surg 1964;108:398-401.Article
7.
Joress SM:  A study of disinfection of the skin: A comparison of povidone-iodine with other agents used for surgical scrubs . Ann Surg 1962; 155:296-304.Article
8.
Osborne NG, Wright RC:  Effect of preoperative scrub on the bacterial flora of the endocervix and vagina . Obstet Gynecol 1977;50:148-151.
9.
Maumenee AE, Michler RC:  Sterility of the operative field after ocular surgery . Pac Coast Oto-Ophthalmol Soc 1951;32:172-183.
10.
Chase RC, Ellis PP:  Iodophors and skin asepsis: Iodophors as skin antiseptics before ophthalmic surgery . Ann Ophthalmol 1970;12:312-317.
11.
Kiffney GT, Hattaway AC:  Povidoneiodine as an ophthalmic antiseptic . Surg Forum 1966;17:434-436.
12.
White JH, Stephens GM, Cinotti AA:  The use of povidone-iodine for treatment of fungi in rabbit eyes . Ann Ophthalmol 1972;4:855-856.
13.
Hale LM:  The treatment of corneal ulcer with povidone-iodine (Betadine) . NC Med J 1969; 30:54-56.
14.
Hale LM:  Povidone-iodine in ophthalmic surgery . Ophthalmic Surg 1970;1:9-13.
15.
Kuwahara Y, Ohta Y, Yamada M:  Experience with PVP-iodine . J Clin Ophthalmol 1962; 16:93-97.
16.
Wille H:  Assessment of possible toxic effects of polyvinylpyrrolidone-iodine upon the human eye in conjunction with cataract extraction: An endothelial specular microscope study . Acta Ophthalmol 1982;60:955-960.Article
17.
Gross A, Cofone L, Huff MB:  Iodine inactivating agent in surgical scrub testing . Arch Surg 1973;106:175-178.Article
18.
Lincoff H, Nadel A, O'Connor P:  The changing character of the infected scleral implant . Arch Ophthalmol 1970;84:421-426.Article
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