[Skip to Content]
[Skip to Content Landing]
October 1984

A Miniature Compliance Monitor for Eyedrop Medication

Author Affiliations

From the Department of Ophthalmology (Drs Kass, Meltzer, and Gordon) and the Division of Biostatistics (Dr Gordon), Washington University School of Medicine, St Louis. Dr Meltzer is now with the Dallas Eye Institute, Duncanville, Tex.

Arch Ophthalmol. 1984;102(10):1550-1554. doi:10.1001/archopht.1984.01040031266033

• We developed an eyedrop medication monitor that electronically records the date and time of each medication administration over a six-week period. It records a medication usage in a 15-minute interval when the cap is removed from the bottle and the bottle is inverted. The electronic components housed inside the bottle weigh 7.5 g, including the batteries, and the total volume of the circuit is 7.5 cc. The monitor resembles commercially available 30-mL eyedrop bottles in size, shape, and weight. The monitor is accurate when tested against known patterns of usage. The electronic eyedrop monitor should be useful in assessing compliance with eyedrop medications.

Riffenburgh RS:  Doctor-patient relationship in glaucoma therapy . Arch Ophthalmol 1966; 75:204-206.Article
Spaeth GL:  Visual loss in a glaucoma clinic: I. Sociologic considerations . Invest Ophthalmol 1970;9:73-82.
Spaeth GL:  Pathogenesis of visual loss in patients with glaucoma: Pathologic and sociologic considerations . Trans Am Acad Ophthalmol Otolaryngol 1971;75:296-316.
Vincent P:  Factors influencing patient noncompliance: A theoretical approach . Nurs Res 1971;20:509-516.Article
Vincent P:  Patient's viewpoint of glaucoma therapy . Sightsaving , (Winter) 1972, pp 213-221.
Worthen DM:  Patient compliance and the 'usefulness product' of timolol . Surv Ophthalmol 1979;23:403-406.Article
Bloch S, Rosenthal AR, Friedman L, et al:  Patient compliance in glaucoma . Br J Ophthalmol 1977;61:531-534.Article
MacKean JM, Elkington AR:  Compliance with treatment of patients with chronic openangle glaucoma . Br J Ophthalmol 1983;67:46-49.Article
Yee RD, Hahn PM, Christensen RE:  Medication monitor for ophthalmology . Am J Ophthalmol 1974;78:774-778.
Kass MA:  Non-compliance to ocular therapy . Ann Ophthalmol 1978;10:1244-1245.
Norell SE, Granstrom PA, Wassen R:  A medication monitor and fluorescein technique designed to study medication behavior . Acta Ophthalmol 1980;58:459-467.Article
Feinstein AR, Wood HF, Epstein JA, et al:  A controlled study of three methods of prophylaxis against streptococcal infection in a population of rheumatic children: II. Results of the first three years of the study including methods for evaluating the maintenance of oral prophylaxis . New Engl J Med 1959;260:679-702.
Hogarty GE, Goldberg SC:  Drug and sociotherapy in the aftercare of schizophrenic patients . Arch Gen Psychiatry 1973;28:54.Article
Sackett DL, Haynes RB, Gibson ES, et al:  Hypertension control, compliance and screening . Am Heart J 1977;94:666-667.Article
Norell SE:  Accuracy of patient interviews and attempts by clinical staff in determining medication compliance . Soc Sci Med 1981;15:57-61.Article
Kass MA, Hodapp E, Gordon M, et al:  Patient administration of eyedrops: II. Observation . Ann Ophthalmol 1983;14:889-893.