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February 1985

Effects of Topical Epinephrine on Experimental Sickle Cell Hyphema

Author Affiliations

From the Department of Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago. Dr Barron is now at Louisiana State University Eye Center, New Orleans.

Arch Ophthalmol. 1985;103(2):280-283. doi:10.1001/archopht.1985.01050020132036

• Experimental sickle cell hyphemas were produced by injecting human sickle cell—β°-thalassemia blood into rabbit anterior chambers. Eyes treated with topical 2% epinephrine hydrochloride showed no significant difference in the duration of the hyphema or in the percentage of sickled cells in the anterior chamber compared with untreated eyes. Topical 2% epinephrine had no apparent sustained effect on intraocular pressure.

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