[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.145.218.90. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
June 1985

Rhegmatogenous Retinal Detachment in Labrador RetrieversI. Development of Retinal Tears and Detachment

Author Affiliations

From the Department of Ophthalmology, College of Medicine, University of Illinois at Chicago (Dr Blair and Mr Dodge); and the Michigan State University College of Veterinary Medicine, East Lansing (Dr Schmidt).

Arch Ophthalmol. 1985;103(6):842-847. doi:10.1001/archopht.1985.01050060102037
Abstract

• We used clinical and pathologic methods to examine ten Labrador retrievers with ocular and skeletal abnormalities. The major ocular findings were axial myopia; cataract; vitreous abnormalities, including liquefaction, detachment, and vitreoretinal traction; retinal tears; rhegmatogenous retinal detachment; and proliferative vitreoretinopathy. The appendicular skeleton showed retarded bone growth, bone dysplasia, and degenerative arthropathy. Vitreoretinal traction appeared to be the cause of the retinal tears because (1) formed vitreous was always attached near the anterior edge of the tear, and (2) vitreous traction caused a retinal ridge adjacent to a retinal tear in a dog that had not yet developed retinal detachment. The pathogenetic sequence of spontaneous vitreous abnormalities, retinal tears, and retinal detachment observed in these dogs has not previously been described in animals, to the best of our knowledge, and mimicked human rhegmatogenous retinal detachment, particularly those associated with giant retinal tears.

References
1.
Schepens CL:  Clinical aspects of pathologic changes in the vitreous body . Am J Ophthalmol 1954;38:8-21.
2.
Teng CC, Chi HH:  Vitreous changes and the mechanism of retinal detachment . Am J Ophthalmol 1957;44:335-356.
3.
Rubin LF:  Hereditary retinal detachment in Bedlington terriers . Sm Anim Clin 1963;3:387-389.
4.
Roberts SR, Dellaporta A, Winter FC:  The collie ectasia syndrome: Pathology of eyes of young and adult dogs . Am J Ophthalmol 1966;62:728-752.
5.
Aaberg TM, Machemer R:  Correlation of naturally occurring detachments with long-term retinal detachment in the owl monkey . Am J Ophthalmol 1970;69:640-650.
6.
Barnett KC, Bjorck GR, Kock E:  Hereditary retinal dysplasia in the Labrador retriever in England and Sweden . J Sm Anim Prat 1970; 10:755-759.Article
7.
Gelatt KN, Veith LA:  Hereditary multiple ocular anomalies in Australian shepherd dogs . Vet Med Sm Anim Clin 1970;65:39-42.
8.
Lavach JD, Murphy JM, Severin GA:  Retinal dysplasia in the English springer spaniel . J Am Anim Hosp Assoc 1978;14:192-199.
9.
Stades FC:  Hereditary retinal dysplasia (RD) in a family of Yorkshire terriers . Tijdschr Diergeneeskd 1978;103:1087-1090.
10.
Carrig CB, MacMillan A, Brundage S, et al:  Retinal dysplasia associated with sekeletal abnormalities in Labrador retrievers . J Am Vet Med Assoc 1977;170:49-57.
11.
Stickler GB, Belau PG, Farrell FJ, et al:  Hereditary progressive arthro-ophthalmopathy . Mayo Clin Proc 1965;40:433-455.
12.
Knobloch WH:  Inherited hyaloideoretinopathy and skeletal dysplasia . Trans Am Ophthalmol Soc 1975;73:417-451.
13.
Blair NP, Albert DM, Liberfarb RM, et al:  Hereditary progressive arthro-ophthalmopathy of Stickler . Am J Ophthalmol 1979;88:876-888.
14.
Blair NP, Dodge JT, Schmidt GM:  Rhegmatogenous retinal detachment in Labrador retrievers: II. Proliferative vitreoretinopathy . Arch Ophthalmol 1985;103:848-854.Article
15.
Schepens CL:  Terminology , in Retinal Detachment and Allied Diseases . Philadelphia, WB Saunders Co, 1983, pp 17-19.
16.
Tolentino FI, Donovan RH, Freeman HM:  Biomicroscopy of the vitreous in collie dogs with fundus abnormalities . Arch Ophthalmol 1965; 73:700-706.Article
17.
Freeman HM, Donovan RH, Schepens CL:  Retinal detachment, chorioretinal changes, and staphyloma in the collie: I. Ophthalmoscopic findings . Arch Ophthalmol 1966;76:412-421.Article
18.
Okun E, Rubin LF, Collins EM:  Retinal breaks in the senile dog eye . Arch Ophthalmol 1961;66:118-123.Article
19.
Foulds WS:  Experimental retinal detachment . Trans Ophthalmol Soc UK 1963;83:153-170.
20.
Mutlu F, Leopold IH:  Experimental retinal detachment: Method I . Am J Ophthalmol 1963; 56:427-432.
21.
Landholm WM, Watzke RC:  Experimental retinal detachment with a sulfated polysaccharide . Invest Ophthalmol 1965;4:42-50.
22.
Freilich DB, Lee PF, Freeman HM:  Experimental retinal detachment . Arch Ophthalmol 1966;76:432-436.Article
23.
Machemer R, Norton EWD:  Experimental retinal detachment in the owl monkey: I. Methods of production and clinical picture . Am J Ophthalmol 1968;66:388-396.
24.
Pederson JE, Cantrill HL, Cameron JD:  Experimental retinal detachment: II. Role of the vitreous . Arch Ophthalmol 1982;100:1155-1159.Article
25.
Wiesel TN, Raviola E:  Myopia and eye enlargement after neonatal lid fusion in monkeys . Nature 1977;266:66-68.Article
26.
Wiesel TN, Raviola E:  Increase in axial length of the macaque monkey eye after corneal opacification . Invest Ophthalmol Vis Sci 1979; 18:1232-1236.
27.
Smith EL, Maguire GW, Watson JT:  Axial lengths and refractive errors in kittens reared with an optically induced anisometropia . Invest Ophthalmol Vis Sci 1980;19:1250-1255.
28.
Reese AB:  Persistent hyperplastic primary vitreous . Am J Ophthalmol 1955;40:317-331.
29.
Schepens CL:  Pathogenesis of nontraumatic rhegmatogenous retinal detachment , in Retinal Detachment and Allied Diseases . Philadelphia, WB Saunders Co, 1983, pp 37-67.
30.
Tolentino FI, Schepens CL, Freeman HM:  The vitreous in peripheral retinal breaks and rhegmatogenous retinal detachment , in Vitreoretinal Disorders: Diagnosis and Management . Philadelphia, WB Saunders Co, 1976, pp 372-399.
31.
Hagler WS, North AW:  Retinal dialyses and retinal detachment . Arch Ophthalmol 1968; 79:376-388.Article
×