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To the Editor.
—Silicone oil was initially introduced into clinical ophthalmology to treat complicated retinal detachment by Cibis et al1 in 1964. By 1967, the adverse effects of silicone oil were thought to be greater than its benefits, and its use subsequently fell into disfavor in the United States.2 In the early 1970s, the use of silicone oil was revived in Europe for the repair of complicated retinal detachment. In recent years, the main complications from the use of silicone oil have been cataract formation, late-onset glaucoma, and keratopathy. Of these, keratopathy has been the most difficult to manage, often requiring removal of the silicone oil.3 Histopathologic studies have shown that the adverse effects on the lens and cornea are due to the mechanical obstruction of the flow of nutrients to these tissues by silicone oil.4In patients who have undergone multiple intraocular procedures, who are
Paylor RR, Peyman GA. A Method to Locate the Silicone Oil-Aqueous Humor Interface. Arch Ophthalmol. 1985;103(12):1782-1783. doi:10.1001/archopht.1985.01050120012004