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August 1986

Muscles as Sense Organs

Arch Ophthalmol. 1986;104(8):1148-1149. doi:10.1001/archopht.1986.01050200054047

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We have become extraordinarily sophisticated in our understanding of the oculomotor system. From both clinical and basic directions, our appreciation of the peripheral and central structures involved in moving the eyes or holding their angle of gaze has grown enormously (eg, see Berthoz and Melvill Jones1 or Howard2 for summaries of recent experimental work and Lennerstrand et al3 for clinical studies). In spite of this sophistication, however, certain fundamental questions remain. For example, what sort of information does the brain use to keep informed of eye position? The traditional explanation, attributed to Helmholtz but, in fact, going back to the early Greeks,4 says that efferent signals sent to the eye muscles are monitored and that this outflowing signal is all that is used. The many proprioceptors in eye muscles and tendons5,6 are not believed to be playing any role in supplying position information in spite of the fact that responses

Berthoz A, Mevill Jones G (eds): Adaptive Mechanisms in Gaze Control . New York, Elsevier Science Publishing Co Inc, 1985.
Howard IP: Human Spatial Orientation . New York, John Wiley & Sons Inc, 1982, pp 176-274.
Lennerstrand G, Zee DS, Keller EL (eds): Functional Basis of Ocular Motility Disorders . Elmsford, NY, Pergamon Press Inc, 1982, pp 3-548.
Grusser O-J:  J. E. Purkyne's contributions to the physiology of the visual, the vestibular and the oculomotor systems . Hum Neurobiol 1984;3:129-144.
Cooper S, Daniel PM, Whitteridge D:  Muscle spindles and other sensory endings in the extrinsic eye muscles: The physiology and anatomy of these receptors and of their connexions with the brain-stem . Brain 1955;78:564-583.Article
Richmond FJR, Johnston WSW, Baker RS, et al:  Palisade endings in human extraocular muscles . Invest Ophthalmol Vis Sci 1981;25:471-476.
Manni E, Bortolami R:  Proprioception in eye muscles , in Lennerstrand G, Zee DS, Keller EL (eds): Functional Basis of Ocular Motility Disorders . Elmsford, NY, Pergamon Press Inc, 1982, pp 55-64.
Carpenter RHS: Movements of the Eyes . London, Pion, 1977, pp 235-239.
Guthrie BL, Porter JD, Sparks DL:  Corollary discharge provides accurate eye position information to the oculomotor system . Science 1983;221:1193-1195.Article
Campos EC, Chiesi C:  Abnormal spatial localization in patients with herpes zoster ophthalmicus: Evidence for the presence of proprioceptive information . Arch Ophthalmol 1986;104: 1176-1177.Article
Scott AB:  Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery . Arch Ophthalmol 1980;87:1044-1049.Article
Goldspink G, Tabary C, Tabary JC, et al:  Effect of denervation on the adaptation of sarcomere number and muscle extensibility to the functional length of muscle . J Physiol 1974;236:733-742.
Ludvigh E:  Control of ocular movements and visual interpretation of environment . Arch Ophthalmol 1952;48:442-448.Article
Steinbach MJ, Smith DR:  Spatial localization after strabismus surgery: Evidence for inflow . Science 1981;213:1407-1409.Article
Steinbach MJ: Inflow as a long-term calibrator of eye position in humans. Acta Psychologica, in press.
McCloskey DI:  Corollary discharges: Motor commands and perception , in Brooks VB (ed): Handbook of Physiology: The Nervous System: II. Motor Control . Bethesda, Md, American Physiological Society, 1981, pp 1415-1447.
Matthews PBC:  Where does Sherrington's 'muscular sense' originate? Muscles, joints, corollary discharges? Annu Rev Neurosci 1982;5:189-218.Article
Matin L:  A possible hybrid mechanism for modification of visual direction associated with eye movements: The paralyzed eye experiment reconsidered . Perception 1976;5:223-239.Article
Von Noorden GK: Burian-von Noorden's Binocular Vision and Ocular Motility , ed 3. St Louis, CV Mosby Co, 1985, pp 5-6, 110-113.