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Article
July 1988

Color Vision Defects in Ocular Hypertension and GlaucomaQuantification With a Computer-Driven Color Television System

Author Affiliations

From the Department of Clinical Ophthalmology, Institute of Ophthalmology, and Electrodiagnostic Clinic, Moorfields Eye Hospital, London. Dr Gündüz is now with the University Eye Department, Konya, Turkey; Mr Perry is in Proserpine, Queensland, Australia; and Dr Weinstein is now with West Virginia University Medical Center, Morgantown.

Arch Ophthalmol. 1988;106(7):929-935. doi:10.1001/archopht.1988.01060140075028
Abstract

• In order to detect early defects of color vision caused by increased intraocular pressure, a computer graphics device and color monitor system were used to measure color contrast sensitivity. The system determines the threshold chrominance of a colored grating in which there is no change in luminance. The study included 13 control subjects aged 10 to 57 years and 19 patients with ocular hypertension or glaucoma aged 20 to 58 years. In the 13 eyes with visual field loss, color contrast sensitivity was profoundly reduced when the grating colors fell on a tritan color confusion line. In the eyes without visual field loss, tritan color contrast sensitivity was reduced to an average level considerably below the extreme limits of the control group. These results were compared with those of other color vision tests and diagnostic criteria for glaucoma. The findings suggest that among the tests used, color contrast sensitivity testing was able to discriminate most effectively between patients who had retinal damage and the normal population.

References
1.
References 9, 13, 16, 17, 29-31, 36, 38, 40, 49.
2.
Epstein DL: Chandler and Grant's Glaucoma , ed 3. Philadelphia, Lea & Febiger, 1986.
3.
Hollows FC, Graham PA:  Intraocular pressure, glaucoma, and glaucoma suspects in a defined population . Br J Ophthalmol 1972;50:570-586.Article
4.
Scott GI: Traquair's Clinical Perimetry , ed 7. London, Henry Kimpton, 1957, p 151.
5.
Neima D, LeBlanc R, Regan D:  Visual field defects in ocular hypertension and glaucoma . Arch Ophthalmol 1984;102:1042-1045.Article
6.
Heijl A, Drance SM:  A clinical comparison of three computerized automatic perimeters in the detection of glaucoma defects . Arch Ophthalmol 1981;99:832-836.Article
7.
Spaeth GL, Varma P:  Assessment of the glaucomatous patient . Eye 1987;1:2939.Article
8.
Sommer A, Pollack I, Maumenee AE:  Optic disc parameters and onset of glaucomatous field loss: I. Methods and progressive changes in disc morphology . Arch Ophthalmol 1979;97:1444-1448.Article
9.
Quigley HA:  The value of the retinal nerve fibre layer examination in the diagnosis of glaucoma , in Kriegelstein GK, Leydhecker W (eds): Glaucoma Update II . Berlin, Springer-Verlag, 1983, pp 129-132.
10.
Iwata K:  The earliest finding of primary open-angle glaucoma (POAG) and the mode of progression , in Kriegelstein GK, Leydhecker W (eds): Glaucoma Update II . Berlin, Springer-Verlag, 1983, pp 133-138.
11.
Arden GB, Vaegan, Hogg CR:  Clinical and experimental evidence that the pattern electroretinogram (PERG) is generated by more proximal retinal layers than the focal electroretinogram (FERG) . Ann NY Acad Sci 1982;388:580-607.Article
12.
Wanger P, Persson HE:  Pattern reversal electroretinograms in unilateral glaucoma . Invest Ophthalmol Vis Sci 1983;24:749-753.
13.
Pabst N, Bopp M, Schnaudigel OE:  The pattern evoked electroretinogram associated with raised intraocular pressure . Graefes Arch Clin Exp Ophthalmol 1984;222:34-37.Article
14.
Trick GL:  Pattern reversal retinal potentials in ocular hypertensives at high and low risk of developing glaucoma . Doc Ophthalmol 1987;65:79-86.Article
15.
Porciatti VB, Falsini B, Neroni M, et al:  Pattern electroretinogram as a function of spatial frequency in ocular hypertension and early glaucoma . Doc Ophthalmol 1987;65:349-355.Article
16.
Weinstein GW, Arden GB, Hitchings RA, et al:  The pattern electroretinogram (PERG) in ocular hypertension and glaucoma . Arch Ophthalmol 1988;106:923-928.Article
17.
Drance SM, Airaksinen PJ:  Signs of early damage in open angle glaucoma , in Weinstein GW (ed): Contemporary Issues in Ophthalmology: Open Angle Glaucoma . New York, Churchill Livingstone, 1986, pp 17-30.
18.
Goldmann H:  Summary of Cambridge Symposium on Glaucoma . Br J Ophthalmol 1972;56:306-308.Article
19.
Biersdorf WR:  The Davidson and Hemmendinger color rule as a color vision screening test . Arch Ophthalmol 1977;95:134-138.Article
20.
Fletcher R, Voke J: Defective Color Vision . Bristol, England, Adam Hilger Ltd, 1985.
21.
Pokorny J, Smith VC, Verriest G, et al: Congenital and Acquired Color Vision Defects . New York, Grune & Stratton, 1979.
22.
Farnsworth D:  The Farnsworth-Munsell 100-hue dichotomous tests for color vision . J Opt Soc Am 1943;33:568-576.Article
23.
Gunkel RD, Cogan DG:  Colorimetry by a new principle . Arch Ophthalmol 1978;96:331-334.Article
24.
Berson EL, Sandberg MA, Rosner B, et al.  Color plates to help identify patietns with blue cone monochromatism . Am J Ophthalmol 1983;95:741-747.Article
25.
Breton ME, Tansley BW:  Improved color test results with large-field viewing in dichromats . Arch Ophthalmol 1985;103:1490-1494.Article
26.
Arden GB, Gündüz K, Perry S: Color vision testing with a computer graphics system. Clin Vis Sci, in press.
27.
Arden GB, Gündüz K, Perry S: Color vision testing with a computer graphics system: Preliminary results. Doc Ophthalmol, in press.
28.
Hart WM:  Acquired dyschromatopsia . Surv Ophthalmol 1987;32:10-31.Article
29.
Quigley HA, Hohman RM, Addicks EM, et al:  Morphologic changes in the lamina cribrosa correlated with neural loss in open angle glaucoma . Am J Ophthalmol 1983;95:673-691.
30.
Quigley HA, Sanchez RM, Dunkelberg GR, et al:  Chronic glaucoma selectively damages large optic nerve fibers . Invest Ophthalmol Vis Sci 1987;28:913-920.
31.
Quigley HA:  Reappraisal of the mechanisms of glaucomatous optic nerve damage . Eye 1987;1:318-322.Article
32.
Drance SM, Lakowski R, Schulzer M, et al:  Acquired color vision changes in glaucoma: Use of 100-hue test and Pickford anomaloscope as predictors of glaucomatous field change . Arch Ophthalmol 1981;99:829-831.Article
33.
Flammer J, Drance S:  Correlation between color vision scores and quantitative perimetry in suspected glaucoma . Arch Ophthalmol 1984;102:38-39.Article
34.
Abe H, Sakai T, Yamazaki T:  Selective impairment of the three color mechanisms isolated by a new color campimeter . Acta Soc Ophthalmol Jpn 1982;87:950-957.
35.
Hamill TR, Post RB, Johnson CA, et al:  Correlation of color vision deficits and observable changes in the optic disc in a population of ocular hypertensives . Arch Ophthalmol 1984;102:1637-1639.Article
36.
Logan N, Anderson DR:  Detecting early glaucomatous visual field changes with a blue stimulus . Am J Ophthalmol 1983;95:432-434.
37.
Lakowski R, Drance SM:  Acquired dyschromatopsia: The earliest functional loss in glaucoma . Doc Ophthalmol Proc Ser 1979;19:159-168.
38.
Pooinoosawamy D, Nagasubramanian S, Gloster J:  Color vision in patients with chronic simple glaucoma and ocular hypertension . Br J Ophthalmol 1980;64:852-860.Article
39.
Drance SM, Lakowski R:  Color vision in glaucoma , in Krieglstein GK, Leydhecker W (eds): Glaucoma Update II . Berlin, Springer-Verlag, 1983, pp 117-122.
40.
Arden GB:  The importance of measuring contrast sensitivity in cases of visual disturbance . Br J Ophthalmol 1978;62:198-209.Article
41.
Atkin A, Podos SM, Bodis-Wollner I:  Abnormalities of the visual system in ocular hypertension and glaucoma: Seeing beyond routine perimetry in glaucoma , in Krieglstein GK, Leydhecker W (eds): Glaucoma Update II . Berlin, Springer-Verlag, 1983, pp 107-116.
42.
Singh H, Cooper RL, Alder VA, et al:  The Arden grating acuity: Effect of age and optical factors in the normal patient, with prediction of the false negative rate in screening for glaucoma . Br J Ophthalmol 1981;65:518-524.Article
43.
Abe H, Hasegawa S, Iwata K:  Contrast sensitivity and pattern visual evoked potential in patients with glaucoma . Doc Ophthalmol 1987;65:65-70.Article
44.
Derrington AM, Krauskopf J, Lennie P:  Chromatic mechanisms in lateral geniculate nucleus of macaque . J Physiol 1984;357:241-265.
45.
De Monasterio FM:  Electrophysiology of color vision , in Verriest G (ed): Color Vision Deficiencies VII . The Hague, Dr W Junk Publishers, 1984, pp 9-28.
46.
MacAdam DL:  Specification of small chromaticity differences . J Opt Soc Am 1943;33:18-26.Article
47.
Silberstein L, MacAdam DL:  The distribution of color matchings around a color center . J Opt Soc Am 1945;35:32-39.Article
48.
Cowan WB:  Discreteness artifacts in raster display systems , in Mollon JD, Sharpe LT (eds): Color Vision . Orlando, Fla, Academic Press Inc, 1983, pp 145-154.
49.
Farnsworth D: The Farnsworth-Munsell 100-Hue Test . Baltimore, Munsell Color Co, 1957.
50.
Phelps CD, Motolko MA:  Contrast sensitivity and glaucoma , in Krieglstein GK, Leydecker W (eds): Glaucoma Update II . Berlin, Springer-Verlag, 1983, pp 103-107.
51.
Bartl G:  Das Elektroretinogram und das evozierte Sehrindenpotential bei normalen und an Glaukom erkrankten Augen . Graefes Arch Clin Expo Ophthalmol 1978;207:243-269.Article
52.
Fazio DT, Heckenlively JR, Martin DA, et al:  The electroretinogram in open-angle glaucoma . Doc Ophthalmol 1986;63:45-54.Article
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