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April 1990

Clearance of Experimental Vitreous Hemorrhage After Panretinal Cryotherapy Is Related to Macrophage Influx

Author Affiliations

From the Department of Ophthalmology, Medical College of Wisconsin, Milwaukee (Drs D. F. Williams, Burke, and G. A. Williams). Dr G. A. Williams is now with the William Beaumont Hospital, Royal Oaks, Mich.

Arch Ophthalmol. 1990;108(4):595-597. doi:10.1001/archopht.1990.01070060143065

• We investigated the effect of panretinal cryotherapy on blood clearance and on the inflammatory cellular response in rabbit eyes with experimental vitreous hemorrhage. Eyes treated with cryotherapy demonstrated less extensive vitreous opacity and more rapid clearance of blood than untreated eyes. The peak inflammatory cellular response measured by counts of radiolabeled cells in the optic nerve was 2.5 times greater in the cryotherapy-treated eyes. Panretinal cryotherapy may promote the clearance of vitreous hemorrhage by stimulating the influx of increased numbers of phagocytic inflammatory cells.

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