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September 1990

Refractive Predictability of Myopic Hydrogel Intracorneal Lenses in Nonhuman Primate Eyes

Author Affiliations

From the Department of Ophthalmology, Emory University, Atlanta, Ga (Dr McCarey), Allergan Medical Optics, Irvine, Calif (Mr Storie and Dr Knight), and the Department of Ophthalmology, Groningen (the Netherlands) University (Dr van Rij).

Arch Ophthalmol. 1990;108(9):1310-1315. doi:10.1001/archopht.1990.01070110126036

• The refractive predictability of myopic hydrogel intracorneal lenses made of lidofilcon A was evaluated in 24 monkey eyes following a microkeratome dissection. All eyes were examined monthly for refractive alteration and clinical appearance during a follow-up period of 7 to 33 months. The refractive yield was measured by retinoscopy and found to be a function of the implant depth. The mean±SD percent of the desired correction achieved averaged 70%±24% at a 36% to 60% depth (n = 8), 54%±22% at a 61% to 79% depth (n = 7), and 12%±14% in implants deeper than at a 79% depth (n = 9). For eyes with implants at a 36% to 60% depth, the predicted vs achieved refractive alteration yielded a correlation coefficient of.97 (88% within ± 3 diopters of the correlation). The refractive outcome remained stable throughout 7 months of follow-up, whereas deeply placed lenses (≥80%) exhibited significant regression in power during this time.

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