[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.111.118. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
January 1994

Oral Imipramine and Acute Angle Closure Glaucoma

Author Affiliations

From the Departments of Ophthalmology, the New York (NY) Eye and Ear Infirmary (Dr Ritch), Northwestern University School of Medicine, Chicago, Ill (Dr Krupin), University of Arkansas for Medical Sciences, Little Rock, Ark (Dr Henry), and St Vincent's Medical Center, Los Angeles, Calif (Dr Kurata). The authors have no financial interest in any product discussed in this article.

Arch Ophthalmol. 1994;112(1):67-68. doi:10.1001/archopht.1994.01090130077021
Abstract

Objective:  To document acute angle closure glaucoma temporally related to ingestion of oral imipramine hydrochloride.

Patients:  Four patients with narrow angles received routinely prescribed doses of imipramine that triggered acute angle closure glaucoma.

Outcome:  Laser iridotomy was successful in all patients.

Conclusions:  Psychoactive drugs should be prescribed cautiously in patients with known narrow angles and should be monitored by an ophthalmologist.

References
1.
Baldessarini RJ.  Drugs and the treatment of psychiatric disorders . In: Gilman AG, Goodman LS, Gilman A, eds. Goodman and Gilman's The Pharmacological Basis of Therapeutics . 8th ed. Elmsford, NY: Pergamon Press Inc; 1990:383-435.
2.
Davidson SI.  Reports of ocular adverse reactions . Trans Ophthalmol Soc U K . 1973;93:1495-1510.
3.
Goldovskaya IL.  Eye complications produced by psychotropic agents . Vestn Oftalmol . 1970;83:54-57.
4.
Lowe RF.  Amitriptylene and glaucoma . Med J Aust . 1966;2:509-510.
5.
Oradell NJ. Physician's Desk Reference . 46th ed. Littleton, Ind: Medical Economics Co; 1992.
×