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May 1995

Corneal Endothelium After Myopic Excimer Laser Photorefractive Keratectomy

Author Affiliations

Dublin, Ireland

Arch Ophthalmol. 1995;113(5):553. doi:10.1001/archopht.1995.01100050015005

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We congratulate Carones et al1 on their work published in the July 1994 issue of the Archives titled "The Corneal Endothelium After Myopic Excimer Laser Photorefractive Keratectomy." Their article confirms our findings reported at the Congress of the European Society of Cataract and Refractive Surgery in September 1993.2

Excimer laser photorefractive keratectomy has been established as a predictable, safe, and effective method to treat myopia up to 6.0 diopters (D). Reports of the effect on the corneal endothelium vary in the experimental setting.3,4 To establish whether routine photorefractive keratectomy, in clinical practice, has any detectable adverse effect on the corneal endothelium, we prospectively examined the endothelial cell counts and morphology of 26 eyes of 26 myopes (ages ranging from 21 to 52 years; mean, 29.8 years) using a noncontact specular microscopy camera (Topcon, Tokyo, Japan). The endothelial photographs from the first and last visits, occurring 6 to

Carones F, Brancato R, Venturi E, Morico A.  The corneal endothelium after myopic excimer laser photorefractive keratectomy . Arch Ophthalmol . 1994;112:920-924.Article
Goggin M, Algawi K, O'Keefe M. Corneal endothelium following photorefractive keratectomy for myopia. Presented at the 11th Congress of the European Society of Cataract and Refractive Surgery; September 1, 1993; Innsbruck, Austria.
Gaster RN, Binder PS, Coalwell K, Berns M, McCord RC, Burstien NL.  Corneal surface ablation by 193-nm excimer laser and wound healing in rabbits . Invest Ophthalmol Vis Sci . 1989;30:90-98.
Talamo JH, Gollamudi S, Green WR, De La Cruz Z, Filatov V, Stark WJ.  Modulation of corneal wound healing after excimer laser keratomileusis using topical mitomycin-C and steroids . Arch Ophthalmol . 1991;109:1141-1146.Article
Amano S, Shimizu K.  Corneal endothelial changes after excimer laser photorefractive keratectomy . Am J Ophthalmol . 1993;116:692-694.