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Article
September 1996

Endogeneous Nocardia Subretinal Abscess

Author Affiliations

Ottawa, Ontario
New Orleans, La

Arch Ophthalmol. 1996;114(9):1147-1148. doi:10.1001/archopht.1996.01100140349023

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Abstract

Nocardia is a gram-positive, weakly acid-fast, filamentous, soil-borne aerobic bacterium that has some morphological and staining features in common with fungi.1,2 Endogenous intraocular nocardiosis is a rarely reported entity.1,2 To our knowledge, the electron microscopic features of intraocular Nocardia have not been reported previously.

Report of a Case.  A 40-year-old black woman with severe renal disease was treated with a cadaveric renal transplant and immunosuppressive medications. Five months later she presented with fever, lethargy, and reduced vision. Funduscopic examination of the right eye disclosed a 4+ vitritis and a 6-mm-diameter well-circumscribed subretinal mass superonasally with an adjacent exudative retinal detachment. A chest radiograph revealed a right upper lobe cavitary lesion. Cranial computed tomography disclosed an occipital infarct, hydrocephalus, and multiple brain abscesses. Meningitis was diagnosed by lumber puncture. A biopsy specimen was taken of the cavitary lung lesion, which showed organisms consistent with Nocardia. She was treated with

References
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Ishibashi Y, Watanabe R, Hommura S, Koyama A, Ishikawa T, Mikami Y.  Endogeneous Nocardia asteroides endophthalmitis in a patient with systemic lupus erythematosus . Br J Ophthalmol . 1990;74:433-436.Article
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Bullock JD.  Endogenous ocular nocardiosis: a clinical and experimental study . Trans Am Ophthalmol Soc . 1983;81:451-531.
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Kamat BR, Dvorak AM.  The electron microscopic appearance of Nocardia asteroides in human lung tissue . Arch Pathol Lab Med . 1984;108:862-864.
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Gregor RJ, Chong CA, Augsburger JJ, et al.  Endogeneous Nocardia asteroides subretinal abscess diagnosed by transvitreal fine-needle aspiration biopsy . Retina . 1989;9:118-121.Article
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