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Nocardia is a gram-positive, weakly acid-fast, filamentous, soil-borne aerobic bacterium that has some morphological and staining features in common with fungi.1,2 Endogenous intraocular nocardiosis is a rarely reported entity.1,2 To our knowledge, the electron microscopic features of intraocular Nocardia have not been reported previously.
Report of a Case.
A 40-year-old black woman with severe renal disease was treated with a cadaveric renal transplant and immunosuppressive medications. Five months later she presented with fever, lethargy, and reduced vision. Funduscopic examination of the right eye disclosed a 4+ vitritis and a 6-mm-diameter well-circumscribed subretinal mass superonasally with an adjacent exudative retinal detachment. A chest radiograph revealed a right upper lobe cavitary lesion. Cranial computed tomography disclosed an occipital infarct, hydrocephalus, and multiple brain abscesses. Meningitis was diagnosed by lumber puncture. A biopsy specimen was taken of the cavitary lung lesion, which showed organisms consistent with Nocardia. She was treated with
Jolly SS, Brownstein S, Samad A. Endogeneous Nocardia Subretinal Abscess. Arch Ophthalmol. 1996;114(9):1147-1148. doi:10.1001/archopht.1996.01100140349023