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June 2017 - January 1929

Decade

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Issue

July 2017, Vol 135, No. 7, Pages 683-824

In This Issue of JAMA Ophthalmology

Highlights

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):683. doi:10.1001/jamaophthalmol.2016.3742
Original Investigation

Incidence of Atrophic Lesions in Stargardt Disease in the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) StudyReport No. 5

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):687-695. doi:10.1001/jamaophthalmol.2017.1121

This multicenter cohort study examines the incidence of atrophic lesions of the retinal pigment epithelium in patients with Stargardt disease as determined by fundus autofluorescence imaging.

Macular Sensitivity Measured With Microperimetry in Stargardt Disease in the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) StudyReport No. 7

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):696-703. doi:10.1001/jamaophthalmol.2017.1162

This study measures and analyzes retinal light sensitivity of the macula in Stargardt disease tye 1 using fundus-controlled perimetry (microperimetry).

Evaluation of Diabetic Retinal Screening and Factors for Ophthalmology Referral in a Telemedicine Network

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):706-714. doi:10.1001/jamaophthalmol.2017.1150

This pre-post study evaluates telemedicine retinal screenings for patients with type 1 or 2 diabetes and identifies factors for ophthalmology referral in the North Carolina Diabetic Retinopathy Telemedicine Network.

Geographic Information Systems Mapping of Diabetic Retinopathy in an Ocular Telemedicine Network

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):715-721. doi:10.1001/jamaophthalmol.2017.1153

This study uses geographic information systems mapping techniques to visualize the locations of patients participating in the North Carolina Diabetic Retinopathy Telemedicine Network, the locations of primary care clinicians and ophthalmologists across the state, and the travel times associated with traveling to the 5 primary care clinics in our study.

Ocular Determinants of Refractive Error and Its Age- and Sex-Related Variations in the Chinese American Eye Study

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):724-732. doi:10.1001/jamaophthalmol.2017.1176

This population-based cross-sectional study reports the ocular determinants of refractive error in Chinese American adults in Monterey Park, California.

Journal Club

Association Between Neurocognitive Decline and Visual Field Variability in Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):734-739. doi:10.1001/jamaophthalmol.2017.1279

This observational cohort study evaluates the association between global neurocognitive impairment and visual field variability in patients diagnosed as having glaucoma or glaucoma suspects.

Association Between Undetected 10-2 Visual Field Damage and Vision-Related Quality of Life in Patients With Glaucoma

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):742-747. doi:10.1001/jamaophthalmol.2017.1396

This cross-sectional study aims to determine the association between quality of life and visual function as measured by 24-2 and 10-2 visual fields in patients with primary open-angle glaucoma.

Detailed Clinical Phenotype and Molecular Genetic Findings in CLN3-Associated Isolated Retinal Degeneration

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):749-760. doi:10.1001/jamaophthalmol.2017.1401

This case series provides detailed clinical, electrophysiologic, structural, and molecular genetic findings in nonsyndromic inherited retinal degenerations associated with CLN3 mutations.

Oral Tyrosine Kinase Inhibitor for Neovascular Age-Related Macular DegenerationA Phase 1 Dose-Escalation Study

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):761-767. doi:10.1001/jamaophthalmol.2017.1571

This phase 1 dose-escalation study measures the safety and efficacy of oral X-82 administered for the treatment of neovascular age-related macular degeneration.

Consensus on Diagnostic Criteria of Idiopathic Orbital Inflammation Using a Modified Delphi Approach

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):769-776. doi:10.1001/jamaophthalmol.2017.1581

This study defines consensus criteria for diagnosis of idiopathic orbital inflammation using a survey of members of the Expert Panel of the Orbital Society.

Use of Corneal Confocal Microscopy to Detect Corneal Nerve Loss and Increased Dendritic Cells in Patients With Multiple Sclerosis

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):777-782. doi:10.1001/jamaophthalmol.2017.1590

This cross-sectional study examines the use of in vivo corneal confocal microscopy to identify axonal degeneration in patients with multiple sclerosis.

Association of Glaucoma-Related, Optical Coherence Tomography–Measured Macular Damage With Vision-Related Quality of Life

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):783-788. doi:10.1001/jamaophthalmol.2017.1659

This study examines the pattern of retinal ganglion cell plus inner plexiform layer loss and its association with the self-reported vision-related quality of life of patients with glaucoma-related macular defect.

Brief Report

Accuracy of Billing Codes Used in the Therapeutic Care of Diabetic Retinopathy

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):791-794. doi:10.1001/jamaophthalmol.2017.1595

This medical record review examines the accuracy of diagnostic, procedural, and therapeutic billing codes used in the treatment of diabetic retinopathy.

Use of Corneal Confocal Microscopy to Evaluate Small Nerve Fibers in Patients With Human Immunodeficiency Virus

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):795-800. doi:10.1001/jamaophthalmol.2017.1703

This study reports on the use of in vivo corneal confocal microscopy to quantify changes in corneal nerve fiber and Langerhans cell density in patients with HIV.

Incidence of Presumed Silicone Oil Droplets in the Vitreous Cavity After Intravitreal Bevacizumab Injection With Insulin Syringes

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):800-803. doi:10.1001/jamaophthalmol.2017.1815

This observational study examines the incidence of silicone oil droplets introduced into the eye through intravitreal injection of bevacizumab.

Invited Commentary

The Importance of Outcome Measure Research in Stargardt Disease

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):704-705. doi:10.1001/jamaophthalmol.2017.1544

Telemedicine for Diabetic Retinopathy Screening

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):722-723. doi:10.1001/jamaophthalmol.2017.1257

Can Population-Based Epidemiologic Studies Still Contribute to the Dialogue on Eye Research?

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):732-733. doi:10.1001/jamaophthalmol.2017.1063

Glaucoma, Cognitive Decline, and Healthy Aging

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):740-741. doi:10.1001/jamaophthalmol.2017.1278

Growing Evidence of the Importance of the Macula in Glaucoma

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):747-748. doi:10.1001/jamaophthalmol.2017.1379

Tyrosine Kinase Inhibitors in Age-Related Macular Degeneration

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):767-768. doi:10.1001/jamaophthalmol.2017.1600

Use of Structural End Points in GlaucomaBeyond Visual Field Loss

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):789-790. doi:10.1001/jamaophthalmol.2017.1657
JAMA Ophthalmology Clinical Challenge

Pigmented Iridociliary Lesion and Increased Intraocular Pressure

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):805-806. doi:10.1001/jamaophthalmol.2016.5128

A woman in her 70s with a history of cutaneous melanoma presented with a pigmented iris lesion. Ultrasound biomicroscopy revealed a mid-low reflective anterior ciliochoroidal lesion centered in the nasal quadrant and extending circumferentially from the 12-o’clock position to the 7-o’clock position. What would you do next?

Bilateral Decreased Vision During Pregnancy

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):807-808. doi:10.1001/jamaophthalmol.2016.5453

A woman presented with bilateral decreased vision, bilateral hyperemic discs, macular edema, and subretinal fluid. What would you do next?

Bilateral Retinal Whitening in a Hospitalized Patient

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):809-810. doi:10.1001/jamaophthalmol.2016.5474

A 35-year-old man was admitted as an inpatient for altered mental status and experienced acute-onset bilateral decreased vision on the second day of hospitalization. What would you do next?

Acute and Painless Monocular Vision Loss in a Human Immunodeficiency Virus-Positive Man

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):811-812. doi:10.1001/jamaophthalmol.2016.5679

A man in his 40s presents with central vision loss in his right eye, bilateral lower leg swelling, a torso rash, reduced hearing abilities, and tinnitus. What would you do next?

Research Letter

Trends in Fluoroquinolone Nonsusceptibility Among Coagulase-Negative Staphylococcus Isolates Causing Endophthalmitis, 1995-2016

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):814-815. doi:10.1001/jamaophthalmol.2017.1826

This study investigates the susceptibilities of CoNS-causing endophthalmitis to fluoroquinolones over a 22-year time period at the Bascom Palmer Eye Institute, Miami, Florida, are reported.

Observation

Intravitreal Melphalan for Treatment of Primary Vitreoretinal LymphomaA New Indication for an Old Drug

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):815-818. doi:10.1001/jamaophthalmol.2017.1810

This case report details the use of melphalan, a medication commonly used for treatment of vitreous seeding from retinoblastoma, in 3 eyes of 2 patients with primary vitreoretinal lymphoma.

Comment & Response

Incorporating Clinical, Histological, and Genetic Parameters for Choroidal Melanoma Prognostication

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):818-819. doi:10.1001/jamaophthalmol.2017.1391

Patient Coauthored History Could Improve Health Record Accuracy

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):818. doi:10.1001/jamaophthalmol.2017.1637

Incorporating Clinical, Histological, and Genetic Parameters for Choroidal Melanoma Prognostication–Reply

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):819-820. doi:10.1001/jamaophthalmol.2017.1393

When Should Emergent Imaging Be Performed?

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):820. doi:10.1001/jamaophthalmol.2017.1427

When Should Emergent Imaging Be Performed?—Reply

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):820-821. doi:10.1001/jamaophthalmol.2017.1430

When Should Emergent Imaging Be Performed?—Reply

Abstract Full Text
JAMA Ophthalmol. 2017;135(7):821-822. doi:10.1001/jamaophthalmol.2017.1433
Correction

Error in Text

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):822. doi:10.1001/jamaophthalmol.2017.1891
Obituary

In Memoriam: William Tasman, MD (1929-2017)

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):823-824. doi:10.1001/jamaophthalmol.2017.1643
Ophthalmic Images

Peripheral Choroidal and Macular Retinal Vascular Nonperfusion

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):e170677. doi:10.1001/jamaophthalmol.2017.0677

This case report describes a a man in his 40s who presented with decreased vision, a dilated pupil, and extensive iris neovascularization in his left eye.

Giant Ocular Surface Squamous Cell Papilloma Treated With Topical Mitomycin C

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):e170681. doi:10.1001/jamaophthalmol.2017.0681

A man in his 70s presented with a recurrent conjunctival papilloma previously treated by multiple surgical procedures.

Ultra-Widefield Imaging of Retinal Hemorrhages Induced by Scleral Depression

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):e171418. doi:10.1001/jamaophthalmol.2017.1418

An infant born at 24 weeks’ gestation weighing 0.75 kg underwent examination with indirect ophthalmoscopy and scleral indentation for retinopathy of prematurity at 14 weeks’ postnatal age.

Man With Femtosecond Laser Starfish Bubbles

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):e171423. doi:10.1001/jamaophthalmol.2017.1423

A man in his 60s had his right eye operated on for cataract using the femtosecond cataract surgery laser platform.

JAMA Ophthalmology Masthead

JAMA Ophthalmology

Abstract Full Text
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JAMA Ophthalmol. 2017;135(7):684. doi:10.1001/jamaophthalmol.2016.3743
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