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September 2016 - January 1929




January 1, 2013, Vol 131, No. 1, Pages 6-124

Translational Science With Clinical Promise

Rituximab for Primary Retinal Lymphoma

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JAMA Ophthalmol. 2013;131(1):95-95. doi:10.1001/jamaophthalmol.2013.1874

Descemet Membrane Endothelial KeratoplastyThe Taming of the Shrew

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JAMA Ophthalmol. 2013;131(1):88-89. doi:10.1001/jamaophthalmol.2013.609

Reaching the Tipping PointFrom Print to Online Publication

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JAMA Ophthalmol. 2013;131(1):90-90. doi:10.1001/jamaophthalmol.2013.1188
Surgical Technique

Management of 2 Intraocular Lenses in the Same Eye

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JAMA Ophthalmol. 2013;131(1):86-87. doi:10.1001/jamaophthalmol.2013.563

In a review of 3 consecutive cases and the surgical maneuvers used in managing them, Emanuelli and Smiddy present options for managing a patient with a dislocated intraocular lens (IOL) in the presence of a second, nondislocated IOL.

Ophthalmic Images

Choroidal Osteomas

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JAMA Ophthalmol. 2013;131(1):124-124. doi:10.1001/jamaophthalmol.2013.568

Anterior Polar Cataract: A Clinical-Pathologic Correlation

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JAMA Ophthalmol. 2013;131(1):21-21. doi:10.1001/jamaophthalmol.2013.565
Small Case Series

Cystoid Macular Edema Associated With Fingolimod Use for Multiple Sclerosis

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JAMA Ophthalmol. 2013;131(1):103-107. doi:10.1001/jamaophthalmol.2013.570

Characteristics of Myelinated Retinal Nerve Fiber Layer in Ophthalmic ImagingFindings on Autofluorescence, Fluorescein Angiographic, Infrared, Optical Coherence Tomographic, and Red-free Images

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JAMA Ophthalmol. 2013;131(1):107-109. doi:10.1001/jamaophthalmol.2013.560

Square Root Transformation of Geographic Atrophy Area Measurements to Eliminate Dependence of Growth Rates on Baseline Lesion Measurements: A Reanalysis of Age-Related Eye Disease Study Report No. 26

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JAMA Ophthalmol. 2013;131(1):110-111. doi:10.1001/jamaophthalmol.2013.572

Rhegmatogenous Retinal Detachment and Bilateral Optic Disc Coloboma in Organoid Nevus Syndrome

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JAMA Ophthalmol. 2013;131(1):111-113. doi:10.1001/jamaophthalmol.2013.573
Clinical Trials

Limbal-Conjunctival vs Conjunctival Autograft Transplant for Recurrent PterygiaA Prospective Randomized Controlled Trial

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JAMA Ophthalmol. 2013;131(1):11-16. doi:10.1001/archophthalmol.2012.2599

Conjunctival autografts offer a promising treatment of frequent and aggressive recurrence of pterygia. Al Fayez compares conjunctival autografts with inclusion of limbal epithelium cells in a randomized parallel-group study.

Concordance of Antiretinal Antibody Testing Results Between Laboratories in Autoimmune Retinopathy

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JAMA Ophthalmol. 2013;131(1):113-115. doi:10.1001/jamaophthalmol.2013.574

Optic Disc Edema From Remote Uveal Melanoma

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JAMA Ophthalmol. 2013;131(1):115-117. doi:10.1001/jamaophthalmol.2013.575

Transient Monocular Vision Loss Due to Churg-Strauss Syndrome Vasculitis

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JAMA Ophthalmol. 2013;131(1):117-119. doi:10.1001/jamaophthalmol.2013.576

Accuracy of International Classification of Diseases, Ninth Revision, Clinical Modification Billing Codes for Common Ophthalmic Conditions

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JAMA Ophthalmol. 2013;131(1):119-120. doi:10.1001/jamaophthalmol.2013.577

Visual Function and Optic Pathway Glioma: A Critical Response—Reply

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JAMA Ophthalmol. 2013;131(1):120-124. doi:10.1001/2013.jamaophthalmol.519

Visual Function and Optic Pathway Glioma: A Critical Response

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JAMA Ophthalmol. 2013;131(1):120-124. doi:10.1001/jamaophthalmol.2013.571

Sensitivity and Specificity of the AdenoPlus Test for Diagnosing Adenoviral Conjunctivitis

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JAMA Ophthalmol. 2013;131(1):17-21. doi:10.1001/2013.jamaophthalmol.513

Sambursky and colleagues compare the clinical sensitivity and specificity of AdenoPlus with those of both viral cell culture and polymerase chain reaction at detecting the presence of adenovirus in tear fluid.

Sensitivity and Specificity of a Point-of-Care Matrix Metalloproteinase 9 Immunoassay for Diagnosing Inflammation Related to Dry Eye

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JAMA Ophthalmol. 2013;131(1):24-28. doi:10.1001/jamaophthalmol.2013.561

Sambursky et al evaluated the sensitivity, specificity, negative predictive value, and positive predictive value of a rapid point-of-care test (InflammaDry) for detection of elevated matrix metalloproteinase 9 levels in diagnosing dry eye.

Clinical Sciences

Intraocular Graft Unfolding Techniques in Descemet Membrane Endothelial Keratoplasty

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JAMA Ophthalmol. 2013;131(1):29-35. doi:10.1001/2013.jamaophthalmol.4

Liarakos and colleagues define various Descemet graft unfolding techniques in Descemet membrane endothelial keratoplasty (DMEK). The retrospective analysis evaluated and categorized the surgical videos of 100 consecutive DMEK cases with at least 6 months of follow-up.

Primary Open-Angle Glaucoma vs Normal-Tension GlaucomaThe Vascular Perspective

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JAMA Ophthalmol. 2013;131(1):36-43. doi:10.1001/2013.jamaophthalmol.1

Mroczkowska et al evaluate patients with primary open-angle glaucoma vs normal-angle glaucoma to determine whether the differences in ocular and systemic circulation warrant separating the two types of glaucoma into distinct entities.

Analysis of Anterior Segment Dynamics Using Anterior Segment Optical Coherence Tomography Before and After Laser Peripheral Iridotomy

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JAMA Ophthalmol. 2013;131(1):44-49. doi:10.1001/jamaophthalmol.2013.567

To evaluate changes in the speed of pupil constriction and in anterior segment parameters after laser peripheral iridotomy (LPI) in 29 patients with angle closure, Zheng and Guzman used anterior segment optical coherence tomography to measure pupil and anterior segment changes in response to illumination before and after LPI.

Vitreoretinal LymphomaA 20-Year Review of Incidence, Clinical and Cytologic Features, Treatment, and Outcomes

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JAMA Ophthalmol. 2013;131(1):50-55. doi:10.1001/jamaophthalmol.2013.569

Prompt diagnosis of vitreoretinal lymphoma (VRL) is essential to a favorable prognosis. Levasseur et al reviewed medical records to determine the incidence and clinical features of VRL and the accuracy of diagnostic procedures.

Radiation-Related Cancer Risk Associated With Surveillance Imaging for Metastasis From Choroidal Melanoma

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JAMA Ophthalmol. 2013;131(1):56-61. doi:10.1001/jamaophthalmol.2013.564

Wen and coauthors estimate the lifetime attributable risk of cancer associated with whole-body positron emission tomography (PET)/computed tomography (CT) and with CT of the chest, abdomen, and pelvis if performed at various frequencies and for different durations for surveillance of patients with primary choroidal or ciliary body melanoma for distant metastasis.

Efficacy of the Screening Algorithm WINROP in a Korean Population of Preterm Infants

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JAMA Ophthalmol. 2013;131(1):62-66. doi:10.1001/jamaophthalmol.2013.566

Choi and colleagues reviewed the records of 314 preterm infants with gestational age less than 32 weeks who were admitted to the neonatal intensive care unit at Chonnam National University Hospital, Gwangju, South Korea, from October 2006 to November 2010 to investigate the efficacy of the WINROP screening algorithm to predict proliferative retinopathy of prematurity.

Ophthalmic Molecular Genetics

Cone Structure in Patients With Usher Syndrome Type III and Mutations in the Clarin 1 Gene

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JAMA Ophthalmol. 2013;131(1):67-74. doi:10.1001/2013.jamaophthalmol.2

Ratnam and coauthors used high-resolution macular images (adaptive optics scanning laser ophthalmoscopy and spectral domain optical coherence tomography) to study macular structure and function in patients with Usher syndrome type III caused by mutations in the Clarin 1 gene.

Socioeconomics and Health Services

Errors in Strabismus Surgery

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JAMA Ophthalmol. 2013;131(1):75-79. doi:10.1001/jamaophthalmol.2013.562

Shen et al use data from a national survey of strabismus surgeons to estimate the prevalence of surgical errors, assess contributing factors, and suggest practices to prevent these errors.

Mechanisms of Ophthalmic Disease

Signaling Pathways Triggered by Oxidative Stress That Mediate Features of Severe Retinopathy of Prematurity

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JAMA Ophthalmol. 2013;131(1):80-85. doi:10.1001/jamaophthalmol.2013.986

Wang and colleagues provide a current understanding of the role of oxidative stress in activating signaling pathways that cause pathologic features in severe retinopathy of prematurity as it manifests in the era of oxygen regulation.


Flashes, Floaters, and Oral Fluoroquinolones

Abstract Full Text
JAMA Ophthalmol. 2013;131(1):91-93. doi:10.1001/archophthalmol.2012.2374

Orbicularis Muscle Aging

Abstract Full Text
JAMA Ophthalmol. 2013;131(1):94-94. doi:10.1001/jamaophthalmol.2013.853
Lessons in Leadership

Interview With Eve J. Higginbotham, MD

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JAMA Ophthalmol. 2013;131(1):96-97. doi:10.1001/jamaophthalmol.2013.1640
Special Article

Blindness and the Age of EnlightenmentDiderot's Letter on the Blind

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JAMA Ophthalmol. 2013;131(1):98-102. doi:10.1001/jamaophthalmol.2013.559

Margo et al explore how a now obscure essay written by Denis Diderot (1713- 1784) during the Age of Enlightenment may represent the turning point in Western attitudes toward visual impairment.