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Clinical Problem Solving: Pathology
Aug 2011

Pathology Quiz Case 3: Diagnosis

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Arch Otolaryngol Head Neck Surg. 2011;137(8):834-835. doi:10.1001/archoto.2011.128-b

Diagnosis: Heterotopic gastric mucosa (inlet patch)

Heterotopic gastric mucosa is characterized by normal, functional gastric glands and tissue in an anatomically aberrant location. First described in 1805, the presence of such tissue in the upper esophagus is also known as a gastric mucosal rest or, more commonly, an inlet patch. The morphological features of the inlet patch may include any combination of gastric-type mucosa of cardiac-, antral-, or corpus-type glands with parietal and chief cells. Inlet patch lesions may be single or multiple and are most often found in the postcricoid portion of the esophagus at, or within 3 cm below, the upper esophageal sphincter.13

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