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Clinical Problem Solving: Pathology
June 2013

Pathology Quiz Case 1: Diagnosis

Author Affiliations


JAMA Otolaryngol Head Neck Surg. 2013;139(6):650-651. doi:10.1001/jamaoto.2013.3234b

Although GISTs are very rare in general, they are the most common mesenchymal tumor of the gastrointestinal (GI) tract.1 They comprise 2% of all neoplasms of the GI tract.1 The incidence of GISTs is approximately 20 persons per million.2,3 Gastrointestinal stromal tumors affect men and women equally with a mean age at diagnosis of 58 years (range, 16-94 years).4 They may present anywhere along the GI tract: existing reports characterize the distribution as the esophagus (2%), stomach (50%), omentum and mesenterium (5%), small intestine (25%), colon (6%), and rectum (9%).4

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