A 60-year-old man presented with a 5-month history of changes in phonation and increased sputum. He denied otalgia, odynophagia, dysphagia, or weight loss. The patient's medical history was negative for malignant disease, and his occupational history was unremarkable. He had no history of tobacco use and consumed 1 glass of wine daily. Examination revealed a 3 × 3-cm mass involving the anterior tongue but not involving the floor of mouth, mandible, epiglottis, pharynx, or larynx. No neck masses or adenopathy were palpated. Whole-body positron emission tomography–computed tomography (PET-CT) revealed an fludeoxyglucose F 18 avid lesion of the anterior tongue, but no other lesions were identified.
McDaniel AS, Burgin SJ, Bradford CR, McHugh JB. Pathology Quiz Case 2. JAMA Otolaryngol Head Neck Surg. 2013;139(6):653. doi:10.1001/jamaoto.2013.3240a